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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for KLK7 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5650 Official gene symbol KLK7 Full name kallikrein-related peptidase 7 Aliases ,PRSS6,SCCE, Gene summary Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.41 Gene position 51487150 - 51479729  Map Viewer Gene orientation minus Gene size 7422 bp Gene sequence >KLK7:complement(23747947..23755368):Length=7422 TGCCAGCCCAAGTCGGAACTTGGATCACATCAGATCCTCTCGAGGTGAGAAGAGGCTTCA TCAAGGGTGCACCTGTAGGGGAGAGGGTGATGCTGGCTCCAAGCCTGACTCTGCTCTCGA GAGGTAGGGGCTGCAGCCTAGACTCCCGGTCCTGAGCAGTGAGGGCCTGGAAGTCTGCAA TTTGGGGCCTTTTAGGGAAAAACGAACTACAGAGTCAGAAGTTTGGGTTCCACAGGGAAG GGCAAGATCGGAGCCTAGATTCCTGGGTCTCTAGGGATCTGAAGAACAGGAATTTTGGGT CTGAGGGAGGAGGGGCTGGGGTTCTGGACTCCTGGGTCTGAGGGAGGAGGGCCTGGGGGC CTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGGGGTCTCGACTCCTGGGTCTGAGGGAG GAGGGGCTGGGGGCCTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGGACCTGGACTCCT AGGTCTGAGGGAGGAGGAGCTGGGGCCTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGG GCCTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGGGCCTGGACTCCTGGGTCTGAGGGA GGAGGGGCTGGGGCCTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGGGCCTGGACTCCT GGGTCTGAGGGAGGAGGGGCTGGGGCCTGGACTCCTGGGCCTGAGGGAGGAGGGACTGAG ACCTGGACTCCTAGGTCTGAGGGAGGAGGGACTGGGACCTGGACTCCTGGGTCTGAGGGA GGAGGAGCTGGGGGCCTGGACTCCTGGGTCTGAGGGAGGAGGGGCTGGGGCCTGGACTCC TGGGTCTGAGGGAGGAGGGGTTGGGGCCTGGACTCCTGAGCCTGAGGGAGGAGGGACTTG GACCTGGACTCCTAGGTCTGAGGGAGGAGGAGCTGGGGGCCTGGACTCCTAGGTCTGAGG GAGGCGGGGCTGGGGGCCTGGACTCCTGGGTCTGAGGGAGGAGGGGTTGGGGCCTGGACT CCTGAGCCTGAGGGAGGAGGGACTTGGACCTGGACTCCTAGGTCTGAGGGAGGAGGAGCT GGGGGCCTGGACTCCTAGGTCTGAGGGAGGAGGGGCTGGGGGCCTGGACTCCTGGGTCTG AGGGAGGAAGGTGCTAGGGTCTGGACTCTTGGGTATGAGGGAGGAGGAGGTTAGGGGTCT GGACTTCTGAGTGTAAGGAAGGAGAGGCCAGAGAAAGGAATTTCTGGGTCTGAGGGAGGA GGGGCTGGGGTTCTGGACCCCTAGGTCTGAGGGAGGAGGGGCTGGGGCCTGGACCCCTGG GTCTGAGGGAGGAGGGGCTGGGGCCTGGACTCCTGGGTCTGTGGGGGGAGGGGCTGGGGC CTGGACCCCTGGGTCTGAGTGGGGAGGGGCTGGGCCTGAATGCTTTCTCCTTCTCAGCTC CAGCAGGAGAGGCCCTTCCTCGCCTGGCAGCCCCTGAGCGGCTCAGCAGGGCACCATGGC AAGATCCCTTCTCCTGCCCCTGCAGATCTTACTGCTATCCTTAGCCTTGGAAACTGCAGG AGAAGAAGGTGAAAGCTGGACTGGGAAGTCTGACCTCACCTCAGGGCCCCCACTGACCCT CTCCAAGGAGTCCCTGAGTCAGAACCCTTCCCTCCTCAAACAGCTTCCATCCTGGGAGGA CCAGACTGTCGGCTGAAGCCCCCGCTCTTCCTGCTTCTGCTGACTCAGGGGGTCTCTGTC CCCTCCAGGCCCTGCCTCCTGTGCTCAGGGTCTCTCTGTGGTTCCCCAGATGAGATGCGC CTCCTGGGTTTCTGAGTGGGCTCCTTCTGTCTGTCTCTATCCCTATCTCTTGCTTTCTCT GTATTTCTCCACACATTTTCATCTGTCTCTGTCCATCTCTGACTCTGGGAATCCCTGAGG TGCAGCCTCAGCCTTCCCCTAATGCTAGCTACCCACGTGCTCCTCCATGTCTCCATCCAG CCCAGGGTGACAAGATTATTGATGGCGCCCCATGTGCAAGAGGCTCCCACCCATGGCAGG TGGCCCTGCTCAGTGGCAATCAGCTCCACTGCGGAGGCGTCCTGGTCAATGAGCGCTGGG TGCTCACTGCCGCCCACTGCAAGATGAAGTAGGTGCCGCCCAAGTCTCTGCTGGAGGTGC ACCAGCGTCTCCAGCTCGCTATGGGGGTGGAAGGGCAGTCTTTCTGTGCCTACGGCTCTA TTCTCCTCTCTCTGGGTCTCTGTCCTCCTCTCTCTGGGCCTCTGTACCCCCTCTCCCTGG GGCTCTGTCCCCCTCTCTCCCTGGCTCTCTGTCTCCCTCTCTCTGGGTCTCTGTCCCCCT CTCTCTGGATCTCTGTTCCCCTCTCTCTGTGTCTCTGTCCCCCATTCTCTCTAGGTCTCT GTTCCCCCTCCTCTCTCTCTGGGTCTCTGTCCCTCTCTCTCTGGTCTCTGTCCCCCTCTC TCTCTGGATCTCTGTCCCCCTCTCCCTGGGCCTCTGTACCCCCTCTCCCTGGGGCTCTGT CCCCCTCTCTCTGGGTCTCTGTCTGCCTTTCTCTCTGGATCTCTGTTCCCCTCTGTGTCT CTGTCCCCTTCTCTCTCCGGGTCTCTGTTCCCCCTCCTCTCTTTCTGGGTCTCTGTCCCT CTCTCTCTGGGTCTCTGTCCCCCTCTCTCTCTGGTCTCTGTTCCCCCTCCTCTCTCTCTG GTCTCTGTCCCTCTCTCTCTGGGTCTCTGTCACCCTCTCTCTCTGGGTCTCTGTCACCCT CTCTCTCTGGTCTCTGTTCCCCCTCCTCTCTCTGTGGGTCTCTGTCCCTCTCTCTCTGGG TCTCTGTTCCCCTCTCTCTCTGGTCTCTGTTCCCCCTCCTCTCTCTCTGGATCTCTGTCC CCCTCTCCCTGGGGCTCTGTCCCCCTCTCTCCCTGGCTCTCTGTCTTCCTCTCTCTGGGG CTCTGTCCCCCTCTCTCTCTGGTCTCTGTTCCCCTCTCTCTGGGTCTCTGTCCCTCTCTC TCTGGGTCTCTGTCCCTCTCTCTCTGGATCTCTGTCCCCCTCTCTCTCTGGGTCTCTGTT CCCCTCTCTCTGGGTCTCTGTCCCCTCTCCTCTCTCTGTGTCTCTCTCCCCCCTCCTCTC TCTGTGTCTCTGTCCCCCCTCCTATCTCTGTGTCTCTCTCCCCCCTCCTCTCTCTGGGTC TCTGTCCCCCCCTCTCTGGGTCTCTGTCTCCCTCTCTCTGGGGCTCTGTCCCCCTCTCTC TCTGGATCTCTGTTCCCCTCTCTCTGGGTCTCTGTCTCCCCTCCTCTCTCTGTGTCTCTG TCCCCCCTCCTCTCTCTGGGTCTCTGTCCCCACCCCGTCCCCCAGGTCTTTGCACACCCT CTCTGTCACAGTGTCTCTTCTGAATCTGTGAATGTCACTCCTCGCAGTGAGTACACCGTG CACCTGGGCAGTGATACGCTGGGCGACAGGAGAGCTCAGAGGATCAAGGCCTCGAAGTCA TTCCGCCACCCCGGCTACTCCACACAGACCCATGTTAATGACCTCATGCTCGTGAAGCTC AATAGCCAGGCCAGGCTGTCATCCATGGTGAAGAAAGTCAGGCTGCCCTCCCGCTGCGAA CCCCCTGGAACCACCTGTACTGTCTCCGGCTGGGGCACTACCACGAGCCCAGATGGTAGG TGGCCTCAGTGACCCAGGAGTGCAGGCCCCAGCCCTCCTCCCTCAGACCCAGGAGTCCAG GCCCCCAGCCCCTCCTCCCTCAGACCCAGGAGTCCAGGCCTCAGCCCCTCCTCCCTCAGA CCCAGGAGTCCAGGCCCCCAGCCCCTCCTCCCTCAGACCCGGGAGTCCAGACCCCAGCCC CTCCTCCCTCAGACCCAGCAGTCCTGGGCCCCAGACCCTCCTCCCTCGGAACCAGGAGCC TGAACAACAGCCCTTCTGGTCCTCGCCCCCATCCTCTCTGACTGACAGCTCTCCCTGCTC CTCCCTGCAGTGACCTTTCCCTCTGACCTCATGTGCGTGGATGTCAAGCTCATCTCCCCC CAGGACTGCACGAAGGTTTACAAGGACTTACTGGAAAATTCCATGCTGTGCGCTGGCATC CCCGACTCCAAGAAAAACGCCTGCAATGTGAGACCCTCCCCCCCAATTCCTCCCCAGTCC TGGGTACCCTGTCTGCATGCCCCAGGGACAGAGCTTGACCCGAGTGACTGGGTACCAAGC CCGGCCTTGCCCTCCCCCCAGGCCTGGCCTCCTCAGCTTTTTCCACCTCATTCTCTGCCT AGGTCAGGGGTGGGAGTTTACTTAGGGGCCAATGTGGCCCTGGGGATGAGACAGAGAGTT TAATAGGGGTGAGAAAGTGGGGGTGGGACCAGGGAAGGAGACTGAGGTGCTGGCCTCAGG CCCAAACCTTAAGGGGGCACCAAAAACCTCAGTGATTGAGATAAATCATAATGCAATATT TAAAAATAAAAATAAAAACTCATGCAGAAGTCCATGATGGACAAAATGTCACATTTTAAA TAAAGAGCAGGTGGATCTTACTGAATTTTCCCTTGCCGTAAGTACTAGCGTGGCTCAGCA CAGCGCTGTACTGGCACTGTCTTCATTTAAAATGTGGATACCATGCCCATCATGCAGTTT TATGTATTACATTTGATTTCGTTAAGTACTGCATTGAAGTATTGTGTATTGCAGTTACTG AGATTTTGTGCCTGAAGCTGATGACTCACTCACCTGACCCTGGCCCTGGTCCCGGGGAAA ACACTCTTTCTCTCCACCTCCTCTCTGTTCCCTCTTTCTGGCCTTTTGTCATCCCCTCTG TTTCTGAACAGTCTTCCCACATCTCTCTTTGTGACATAATTTCATTTCATTCTTTTCCTC TTTGTTTTTTCTCTGTGTTGAGCTAGCTTGCTCTCCCTCCCTTGTTCTCTCTCCATGCCC TCCTCTCTGCTCTCTGTCTTCTCCCTCTTTCTCTTGCTTCTCTCTCTCTCCTCCCCTCCC TCTCTCCTCTCCCTGCCCCCCTGCTCTCTCTTTTTTCCTCTCTCTCTGTCTCCTCTCTGG CCCTCTCCTCTTTCTCTCTCTCCCCCACTTCTCTGTCTCTCTTCATCTCTCTCCCTCATC TCTCCTTGCCCCCTCCTTTTTACTGTCTCTCTCTTTCTCTTTCTTCTATCTCTCTCCTCT CCCTGCCGCTCCCCCATCTCTGTCTTTCTTTCTCTCTCTTTATTCTCCTCCTCTCTTCCA GTCTCTCTCTCCTCTCCCCACCCCCACCCCATCTCTCTCCCCACACCTTCCCCCCCTTTC TCTTTGTCTCTCTCTTCTCCCTCTTTCTTCTCCACCCCCATCTCTCTCTCTCTTCTCTTC CCACACCCTCCCCATCTCCCTCATCTCTTTGTCTGTCTCTCTTCTCCCTCCTTCTTTTCC ACCCCCATCTCTCTGTCTCTCTCTCTCCCCATACCCTTTCCCTCTTCCTCATCTCTCTTT GTCTCTCTCTCCTTTCCCTCTTTCTTCTCCACCTCCAACTCTCTCTGTCTCTCCACACCC ATCCTCCTTGCTCACATCTGCACCTTCAGCTGTCAGGGGATGTGGGATGGTGAGTGTTAG GGATAGAGGAGATGGGAGAGAGATGACTGTCCTAGAGAATAGGGTGTTCCCCTTCTCCCC TGGTGAGGGCCAGTTTCATGAATGTGCAAGCTCTGCACGGACACAGAGCCCCACACTCAG AAGGGTCTCAAACTTAGTCTAATGCATTCCTGCTGTTGTCTTGAAATTCTCAATAATTTT TGAACAAAGGGCCCTGCATTTTCGTTTTGCACCAAGTCCTGTAAATTATGTAACTGGTCT TCACCCTGGTCTCCGAGACCATCGTGTCCCCCTTTCCTGCGCCACAGGGCACGCATCCAC CCCTTGGAGATGATGTTCCTTCTCCCACTAGCTTGGAGCAGGGTCCTTAACATTGGAAAA TAAAGAGTGCTCTGATCCTGGAAGCCCCACCCCTTCTCTGCAATTGGTCTCATTGGCCAA GGGTCAAACCAGTGTCTTCAAAGGACCTAGTGTGTCCCTAGCACTAGCTCTCCCATTAGT CCCCAGAGACAATGAGTCTCTTCTCATTGGCTATGGTGGAAGTCCATAATCTGCAAGACA AAGACCGATAACTGAGGAATGTATGAGAATGAGTTGGGCTTTGATCTGAAGCCAAAGTTA ATCTCCGGCTCTATTCCCTCTAGGGTGACTCAGGGGGACCGTTGGTGTGCAGAGGTACCC TGCAAGGTCTGGTGTCCTGGGGAACTTTCCCTTGCGGCCAACCCAATGACCCAGGAGTCT ACACTCAAGTGTGCAAGTTCACCAAGTGGATAAATGACACCATGAAAAAGCATCGCTAAC GCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAAAATGCACAGGAGTGAGGACGCC GATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATATTTAAACCAACCT CATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAAAGAA ACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAAC TGGACGTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTC ACCACCTTTGACCCAGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCA AAATGTAGAACAAGACTTGAATTTACCATGATATTATTTATCACAGAAATGAAGTGAAAC CATCAAACATGTTCCAAAAGTACCAGATGGCTTAAATAATAGTCTGGCTTGGCACAACGA TGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTGCAATGCAGTGATGCAATCT TGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCAGCCTCCCAAG TACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTAG AGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCAC CCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAA TGATATTACAAACCTATTAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAAC ATTTAGGCTATAGGATGTTAAATGACAAAAGGAAGGACAAAAATATATATGTATGTGACC CTACCCATAAAAAATGAAATATTCACAGAATCAGATCTGAAAACACATGTCCCAGACTGC ATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTTTCCTTGAATGTGCACT TTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCTGAAGA OMIM ID 604438