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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MMP26 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID56547
Official gene symbolMMP26
Full namematrix metallopeptidase 26
Aliases,MGC126590,MGC126592,
Gene summaryProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15
Gene position5009424 - 5013659  Map Viewer
Gene orientationplus
Gene size4236 bp
Gene sequence
OMIM ID605470