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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSG3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5671
Official gene symbolPSG3
Full namepregnancy specific beta-1-glycoprotein 3
Aliases,-,
Gene summaryThe human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM]
LocationChromosome: 19   Locus: 19q13.2
Gene position43244668 - 43225794  Map Viewer
Gene orientationminus
Gene size18875 bp
Gene sequence