Entrez gene ID | | 56852 |
Official gene symbol | | RAD18 |
Full name | | RAD18 homolog (S. cerevisiae) |
Aliases | | ,RNF73, |
Gene summary | | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p25-p24 |
Gene position | | 9005159 - 8918880 Map Viewer |
Gene orientation | | minus |
Gene size | | 86280 bp |
Gene sequence |
| |
OMIM ID | | 605256 |