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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMA6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5687
Official gene symbolPSMA6
Full nameproteasome (prosome, macropain) subunit, alpha type, 6
Aliases,IOTA,MGC22756,MGC2333,MGC23846,PROS27,p27K,
Gene summaryThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q13
Gene position35761574 - 35786680  Map Viewer
Gene orientationplus
Gene size25107 bp
Gene sequence
OMIM ID602855