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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMB4 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5692 Official gene symbol PSMB4 Full name proteasome (prosome, macropain) subunit, beta type, 4 Aliases ,HN3,HsN3,PROS-26,PROS26, Gene summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq] Location Chromosome: 1   Locus: 1q21 Gene position 151372041 - 151374412  Map Viewer Gene orientation plus Gene size 2372 bp Gene sequence >PSMB4:2860683..2863054:Length=2372 TTTTTTCTGCTACCGTGACTAAGATGGAAGCGTTTTTGGGGTCGCGGTCCGGACTTTGGG CGGGGGGTCCGGCCCCAGGACAGTTTTACCGCATTCCGTCCACTCCCGATTCCTTCATGG ATCCGGCGTCTGCACTTTACAGAGGTCCAATCACGCGGACCCAGTAAGTTCTCGGCGCTT TCGTTTGCGTAGCGGGAGGGACCGTGGGGCCTGGTGCTGCCGGCTGGTTTTGAGAGCCCG GGAAGGTGAGGCGGGGACCCCGGGGGCGCGCGAACGGCAGGGGAGCTCAGGGCGCGGAGT CCTGGAGAATGCAGAATAATTGGAAGGAATTATAGAAAATCAGAAGCGCAGCTCAGTGCG CGGAAAGAGGGCGCAGTCCATCCCCCCTCTCAGCTCCCACCGTTCTCACTCTTTAGGAAC CCCATGGTGACCGGGACCTCAGTCCTCGGCGTTAAGTTCGAGGGCGGAGTGGTGATTGCC GCAGACATGCTGGGATCCTACGGCTCCTTGGCTCGTTTCCGCAACATCTCTCGCATTATG CGAGTCAACAACAGTACCATGCTGGGTGCCTCTGGCGACTACGCTGATTTCCAGTATTTG AAGCAAGTTCTCGGCCAGATGGTGTAAGTCATCCAGAGAACAGGAGAGTGGTTCCCAAGT AGAGAGGGGAGTCCCCTGTTTTTTATTCCCTTCGATGGGATGGGGGGACTTGTTGCAGCG GGGGACTGGAAGAGTTGTTGGAGGTGGGCGATCTGTGTTTGCAATAAAGTTTTTGGCATT AGGTGTAAAATGGGGGAAGGTGTGGTAACTTCTTTTGGGGATGGGTGGAGACCCCGACTT AATTCTCTCCCTTTTCTCACAACCAATTCCTTTTAAGGATTGATGAGGAGCTTCTGGGAG ATGGACACAGCTATAGTCCTAGAGCTATTCATTCATGGCTGACCAGGGCCATGTACAGCC GGCGCTCGAAGATGAACCCTTTGTGGAACACCATGGTCATCGGAGGCTATGCTGATGGAG AGAGGTTCATATGAATACAAATAACTTATTTCCTTTACCACCCAACCTAGTACCTGTGTA GTATCTCTTCTGTCTCTTCTCCCCAAGTGAATCCCACTTTAACTCAGACCCCATGGTCCC CTTCTTCAGCTAAGATGAATCTAAGGTGAAATGAGTTTTGACCCATTGTGTCCTGTTAGC TTCCTCGGTTATGTGGACATGCTTGGTGTAGCCTATGAAGCCCCTTCGCTGGCCACTGGT TATGGTGCATACTTGGCTCAGGTAAGTAGTAAGTCTAGAGGTGGGGGAAAGGGAAGACAA AAGGAAATGGATTAGTGGTTGTCTGCTTTTCTCCTGAAATTCTGATATGAGGGATGGGCT GGGATCGCTATTACTGGGCAGATGGTTTTCTTTGTAGTCTGGGGGCTGTAGGTGTTGACA CTGATTCCAGTGACAAGATGACATGACTGGGAGTCAGTAGACATGCAAAGAGAGGACACC CTAGAACTTCTTCCTGAAGTGGCTCTTAGCTTATTTTCTAAGCAGAGTTCATTCTGGTGA GGCAAGAAGTAGAATGTCATCTTTCACTCTAATGCTTTTTATACCATAGATTTGAGACAA CTAGCCTGTTATTCAGCCCAATATCCCCCCATGGTTTTCCCCCAATCTCCCTAGCCTCTG CTGCGAGAAGTTCTGGAGAAGCAGCCAGTGCTAAGCCAGACCGAGGCCCGCGACTTAGTA GAACGCTGCATGCGAGTGCTGTACTACCGAGATGCCCGTTCTTACAACCGGGTGAGGGAT GTGCTGGGAACCTAATTGGCGGGCTCTGGCTACTTGCAATCCCTGGGTCTCTATGCTTTG AAGAACAGATTGCCTTACTTGTGTGACTCCTATTTTCACATTGGGGAAGACCTCCACCTG ACCTTTCATTTAAGGACTTAAGGCGTGGGCATTATTGAATGCTCTGCTTTCTTCCAGTTT CAAATCGCCACTGTCACCGAAAAAGGTGTTGAAATAGAGGGACCATTGTCTACAGAGACC AACTGGGATATTGCCCACATGATCAGGTGAGTAATAGGGAAAAAATTGGTGACAGACTTG GGAGGTCTTTGGCTTACACTAAGCTGGGCTTTTCTGGGAGGCTCACCCAGGAAAATTTTC TGGGTGGAAAGTTTTGGTTGGACAGTACAGCTATTTTTAGGAATTGATCCCTTTATGCTT CACAATTTTATTATTCTGTCTTCCTTTTTTAGTGGCTTTGAATGAAATACAGATGCATTA TCCAGAACTGAAGTTGCCCTACTTTTAACTTTGAACTTGGCTAGTTCAAAGATAGACTCT TCTTTTGTAAAGTAAATAAATTCTTCAAAATG OMIM ID 602177