Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMB5 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5693 Official gene symbol PSMB5 Full name proteasome (prosome, macropain) subunit, beta type, 5 Aliases ,LMPX,MB1,MGC104214,X, Gene summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 14   Locus: 14q11.2 Gene position 23504429 - 23495060  Map Viewer Gene orientation minus Gene size 9370 bp Gene sequence >PSMB5:complement(4495060..4504429):Length=9370 ATGGCCGACCTCACTTCCCTTACGCAACATGGACGTTTTCAGTCACTTCCTGTGATTTTG AGGTTATTCTGATCCAGGACTACTTGCATGACCAAAGCCAAGATGGCAGGTACGTCCTTT TAGAATTTAAGGTTAGTGAAGCCATCTATTTCCCCGACCCCCTTCAGTGAAAATGGTCTT TCGCATCTGGCCCTTCTTTTTGGAGGCGTGCTTGCCAGCAGTCAAAATGGCTCCATTCCG GAATAGATTTAATAGGAAGTGAAGCTGTGACGGCGAGGCGTTGCCCGGCCTATCTTTGCT AGGCGTTCTCAGAATTAGTTCTTTCTGCCCACACTAGACATGGCGCTTGCCAGCGTGTTG GAGAGACCGCTACCGGTGAACCAGCGCGGGTTTTTCGGACTTGGGGGTCGTGCAGATCTG CTGGATCTAGGTCCAGGGAGTCTCAGTGATGGTCTGAGCCTGGCCGCGCCAGGCTGGGGT GTCCCAGAAGAGCCAGGAATCGAAATGCTTCATGGAACAACCACCCTGGCCTTCAAGGTG TGGAGCCAGCCCCCTTGCCAGGCTGAGTACTGAACGCCCGCGACTTGCCTGGCCTCCCAG CCTGACCGGAGTTTGCGGTGGCCTTGGCCACCAACCCAGGCGGAGGCTGGGTCCTCTCGT TCGGACCGCAGCAGTTTTGCTGTCTCATTGGCCCAGGAGGCCCCTGTCTTTGCTCTGGTT GGAAAGGGTGGCGGTGGGGCCGGGGGTAAGTCGGGGGAGGAAGGTGAGGCCTCTTGGGTT GATTCCTAGGCGACCCCAGGTTGCTGCTGTTCAGGATCTTCTAGCTGGGAAAGGCCGCAA CAACAATGAATCTTGGCCGAGGGAAGGCTATTGTAAACGTTTACCAAAGTTTTGGAAACT GGGCGGCCCCTCAAGGCAGGGGTAACTGAAACTGGCATGAAGGGGAAGCGTGGTGAGGGT AAGCATTGTACTAAGAATCAGACATTTGGGGTTCCTTGCCCAGCTCTGCAATAACTAGCT CTAGATTGAGAAATCATTTGATTTCATTGAACCTGTTTCCTCATCTATAAAATGATTTGT TTTTTTTTTTTTTTTGAAACAGGGCTTTTCGCTGTCGCTCAGGCTGGAGTGCAGTGGCTC CAGCGCCTCAGCCTCCAGAGTAGCTGACACTATAGGCACACACCACCACGACAGGCTAAG TTTTTTTACTTTTTGTAGAGATGGATCTCCCTGTGTTGCCCAGGCTGGTCTCCAGCACCT GGCCTCAAGCGGTCCTCCCGCCTTGGTCTCCCAAAATGCCTGGGTTACAGGAGTGAGCCA CCACGCCCATCCTATAAAATGAATTTAATATGGGTTATATCCATGTCAAGGGATTGATGT GAAGCTCGGGTGACATTAATATATGGTGAAGTATAGAAGTATACTGTGAAGTATAAAAGG ACGGAGAAAGAGATGTGCTGGGTTTGGATTGATGCAAAAAGAAGTATGTAGGAGTGTTTT TGTGGTCTTATGTGGCCTGTTTTGTGTTTTCCTCTGATCTTAACAGTTCCGCCATGGAGT CATAGTTGCAGCTGACTCCAGGGCTACAGCGGGTGCTTACATTGCCTCCCAGACGGTGAA GAAGGTGATAGAGATCAACCCATACCTGCTAGGCACCATGGCTGGGGGCGCAGCGGATTG CAGCTTCTGGGAACGGCTGTTGGCTCGGCAATGTCGAATCTATGAGCTTCGAAATAAGGA ACGCATCTCTGTAGCAGCTGCCTCCAAACTGCTTGCCAACATGGTGTATCAGTACAAAGG CATGGGGCTGTCCATGGGCACCATGATCTGTGGCTGGGATAAGAGAGGCCCTGGTGAGTT AAGCTGCAACCACATGATCCTTGGGCTGACACTACAGTGAGGAGGGGTTGGATGGACAGA TGAATTAAAGGGCTTGGTGTCAATGCTGAAGAAGTGTAATTAGGTCCTTAGCCCTTCCTT CTCTCTTTTTTTTTTTCCTGTTTTTTTAGACTGTGTCTCATTCTGTCGCTCAGGCTGGAG TGCAGTGGCATGATCTCAGCTCACTGCAGCCTCCGCCCCCAGGTTCAGGAATTCAAGACC AGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCCGGCGTG GTGGCGGGCGCCTGTAATACCAGCTGCTCAGGAGGCTGAGGCATGAGAATTGCTTGAACC CAGGAGGTGGATGTTGCAGTGAGCAGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAG AGTGAGACTCTGTCTCAAAAAAAAGAATTTAAGAATTCGTTGAAGGCCGGGCGTGGTGGC TCACTCCTGTAATCCCAGCACTTTGGGAGGCTGAGACAGTGGATCACGAGGTCAGGAGAT CGAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACCAAAAATACAAAAAATTAGC CAGGCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATAG TGTGAACCCAGGAGGCGGAGCTTGCAGTGAGTCGAGATGGTGCCACTGCACTCCAGCCTG GGCAACAGAGCGAGACTCTGTCTCAAAAAAAAAAACAAAAAAAAGAATTCGTTGAATCCC ACATGTGGCAGTAGTGCTATTTCAAGTGTTCATTGACCATGTGTGGCTTGTGGCTACTGT ATTGGACTCTAATATATGGTTGTCCCTCAAAAGTTAGTCATTTCTCTTCTGTTTTTTTCT TTTTTTCTTTTTTTGAGATGCAAAGTTTCACTCCGATCGTCCAGTCTGGCGTGTAATGGC ATTGTTTCAGCTCACTACAACCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGCCGCAGTC TCCCAAGTACCTGGGATTACAAGCGCCCACCAGCATGCCCAGCTAATTTTATATTTTTAG TAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAAATCCTGACCTCAGGTGATT CACCCGCCTCAGCCTCCCAAAGTGCCAGGATTAAAGGCGTGAGCCGCTGCACCCGGCCTC TTCTCTTTTTTTCTTTAGAGAGTCTTTGGCCTAGAAGGGGCCTTTTGGGCTCCTCTCTTT TTTGAGGGGGTGGGGATGGAGTCTCGCTCTGTCGCCCCGACTGGAGTGCAGCGGCGGGAT CTCAGCTCACTGCAATCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAACCTTCCA TGTAGCTGAGACTACAGGCATATGCCACCATGCGCGTCTAATTTTTGTATTTTTAGTAGA GACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCC CACCTCAGCCTGCCAAAGTGTTGAGATTACAGGAGTGAGCCATTGCGCCTAGTCCTGGGC TCATTTCTTTTATTTCTTTGCTGGTTATAATCACCCTTACAATCATGCTAGGTCCGGTTC TATCATCTCTGAAAATAAGTTCCTTAGCCTGTTTTTCCTTTCCAGCATTTAAGAAACTTG CCAGACAGTTCAACTTTGTATTTAATGTCATTTCCTCATCAGCCAGTTTTGAATTGCCCG TTTAGTAAAGTTGGAGTATAGCTAGTCACCTTCTAATTTTCCCTTCCATATGCTTAAAAA TAATTATTCTTTCCTCCTTTTGATTTTGCTTCATTCATTTACCTGCTTACTAAATACCTA GTTATCTTATAGAACAATTATAGGGTACCTACCACTTTTTCACTTGCTTTCAAACGAGAA TAGAAAGGGCTGTAGGGAGTATCCACTTACTACCCAATGGAGGATGAAAGGAAATTAAAA ACCGGATGTGAGAGAGGAGCTCACTTTGTTACTTTGGAAATTGAGATGCTTTTCTCTGAA AGGTGGGAAAAGACAGTTCCATACATTTTACGTGATCCAGGGAAGCATTTTGGAAATGTT GCTTTGAACCTTTAGCTGGCGGATTTGTTCTAGGTGATGGAAACAGTGTAAAAGAGTACA GGGACCGGGTAACAAGGAAAATCCAGGGAGACTGAGCATCATTTAAACAGTGCCTTCTTC AAGAGGCCTTCCTGATGACCCTGTCCCATTCATTGTGAGTCAGCCCCTTGCCTCATATTA CAGTTGGCCCTTGAGCAACATGGGTTTGAATCACTCAGGTCCACTTATACGCAGGTATTT TTCAACCTAATTCTGATTGAAAATACACATTCCCAGAATTTGAAACCCAAATATACAGAG GACCAATTTATTTATTTATTTATTTATTTATTTTTGAGATGGAGTTTTCCTCTTGTCACC CATGCTGGAGTGCAATGGCGCGATCTCAGTTCATTGCAACCTCCACCTCCTGGGTTCAAG TGATCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGACACCCGCCACCCTGCCAGC TAACTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTAAAC TCCTGACCTCGGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGTGGCGTGAGCCAC CATATCTGGCCAACTTTTCATATATGCAGGTTCTGCAGGGCCAACTTTGGGACTTGAGTG TGCATAGATTTTGGTATATGCAGGGGTCTTGGGACAAATCCCCTTCATATACCAAAGGAT GACTAGTTAACCCAAGGCTGAATAAGATAAATAACCTTTTTTTTTTTTTATTGAGACGGA GTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCATCTCTGCTCACTGCAAGCTCC GCCTCCCGGATTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTG CCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACTGTGTT AGCCAGGATGGTCTCAATCTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGC TGGGATTGCAGGCGTGAGCCACAGCTCCTGGCCTGATAAATACCGTTTTTAAAAGAACCA GTTGGCTGGGCATGGTGGCTCATGCCTGTAATCTCAGCACTTTGGGAGGCCGAGATGGGT GGATCACCGGAGATCAGGAGTTCGAGACCAGCCTGACCAACATGGTGGAACCTTGTCTCT ACTAAAAATACAAAATTATTGGGAGGCCGAGGCGGGCGGATCACGAGGCCAGGAGATCGA GACCATCCTGGCTAACACGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGG GCGTGGTGGTGGTCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGT GAACCCAGGAGGTGGAGCTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGACTGGGC AACAGAGCAAGACTCCATCTCAAAAAAAAAAAATACAAAATTAGCCGGCTGTGGTGGCAC ATGCCTGTAATCCCAGCTACTCAGGGAGATGAGGCAGGAGAATCTCTTGAACCCTGGAGG TGCATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCAATCACTTGAACC TGGGAGGCAGAGGTTGCAGTAAGCTGAGATTGTGCCATTGCACTCCAGCTTGGGAAACAA GAAAGAAACTTTGTCTCAAAAATCAGTCAGTCAATCAATAAATAAAAAGAACCAGTCAAA TGCGGAAGGAGTTTTGAGGAGGAAGAGATTACTTATGATGGGAGGAATTGGGGAAGACTT CATGGATTGGTGGTGGTTGTCCTGGATGTAAAAAAGGGAAAGGGAACATAACAAAGAAAG GGAGGAAAGAAGCATGAGCTTTTGAGGAGTAACTGAAAGTCCAGTTTAATTGGAACTAAG TGGGTGAAGGGGAATAGTGAGCCATAAAGCCAGAAGGGTACTTTGGAACCAGATGATGAC CCCCCTCTAGGCAAGAGAGCATGGCACTGGGGCTGAGGAGGGGCCAGAGAAAGGAGTAAG GTAGACATCAGAATCACCTGAACCTGAAAACCAATAAGGGCAGAGGTGCTCAAGCTGGCT TGCATTAAAATCACCTGGGGGACTTAAAAAACAAGTTCCATACCTGTTTCCCACCCCACA CCAGTTATAAAAAATACCTAGGGTAAGTCCTGTGCATTTTTGAAAAAAATCTTTGTTAGA TGACTCTAGTGCACAGTGAGATGTGAGAATCACTGAAACAGGAAAAAGAGTAGTGATGCT ATTGGCAGAATTTCAGAAGACAGGAGGAAGCGTGGGTTTGTGGCGCACAAGAGAGATGAG TGTGGTAGGTAATGGAGAACCACTGGTATCTAAGTTTAGGAAGTTTGAATCTGTACATGA TGACAAAGACATCCAGCTGGAGGGATCCAGTAGGCAGTTGGGATTGAACACTTTGTCTAA ATTTTCATCTGTACCAAAAGTCAGCTAGTTTTTTCATAAAGGGCCAAATAGTAAATATTT TAGGTCTGCAGGCCTAAATCTTTGTCTCAAATACTTAACTCTGCCGGTGTTGCACAAAAC AACCATAGACAGTATGGAAACAGTGGCTCTGTTCCAATAACATTTTAATTACAAAAATAA AGGCAGTTGGCCTGGCCAAACCCTGGTCTATACCAGCAATAGAAATATAATGTGAGCCAT ATATGTAATTTTACATTTTATACTAGCTACGCTTTTAAAATTAAAAAAAATTAATTTCAA TATATTTTGTTTAACCTAATAAATCCAAAATATTATGTTAGCAGGTAGTACTAGTTCATT TCAAATGCTCAACTAGTCCTGTGTGGCTAGTGGCTACCATATGGACAGTGCAGGTCTTTA CAATGTGATTACAAACTCTAGGCTTTATTATCCTCCTGTGTAAAGTATGTCTTGTTCTCC AGATAGTCTAAACTCTTTGAGTTCTGGCATTATGGAGTTTGTTTTTCTGTCACACAGGCT GCAGTGCAGTGGCATAATCACAGCTCACTGTAGCCTCAACCTCCTGGGCTCAAGTGACTG GGATTATGGGGTCTTTTGATGGGGGAGTGGGGATTATGTTTTGTTTGTTTGTTTTTTGAG ACAGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCA AACTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCCGCCTCCTGAGTAGCTGGGATTA CAGGCATGCGCCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGACAGGGTTTCTCCA TGTTGGTCAGGCTTGTCTTGAACTCCTGACCTCAGGTGACCCACCTGCCTCGGCCTCCCA AAGTGCTGGGATTACGGGTTTGAGCCACTGCGCCTGGCCGGGGATTATGTTTTAAATGTT ATCTTTCACAGTGTCTGAAGTTCTGTGCTTGAAACCTAAGTCATTTGGAATGTACTTGTT TTGTGGGTGTGCTGAGAGGATCGGCAACATGGCAAGGTAGTTATTATAATATAAGGTGAG ATGGGGTGGTATGTTGTAGAATCCTGGAGTCTTAATATTAAATTTTATTCCTTCAGGTTT TTTTTTTTTCCTGAAGACAGCATCTCAGTCTGTTGCCCAAGCTGGAGTGTGGTGGTGTGA TTATAGCTTACTGCAGCCTGCAAGTCCTGAGCTCAAACAATCCTCCTGTTTCAACCTCCC ACAGACATGCACCACCACACTCAGCTAGCTTTTAAAAAAATAATAATAATTTTATAGAAG TCCTATCTTGTATTTATGTTGGCTTCCCTGGGTTTCTCTTTTATATATATATATATTATT TTATTTATTTATTATTATTATTATTATTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGT CTCCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACCGCAAGCTCCGCCTCCCGGGTT TACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTGCAGGCGACCGCAACCACA CCTGGCTAATTTTTTGTTTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGATC TCGATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGC GTTAGCCACCGCGCCTGGCCTATTTATTATATTATTTTGAGACAGCGTTTCACTCTTGTT GCCCAGGCTGGAGTGCAATGGCGCGATCTTGGCTTACCGCAACCTTTGCCTCCCAGGTTC AAGTGATTCTCCTGCATCAGCCTCCTGAGTAGCTGGGATTATAGGCATGTGCCACCACGC CTGGCAAATTTTGTATTTTTAGTAGAGATGGGGTTTCTTCATGTTGGTCAGGCTGGTCTC AAACGCCTGACCTCAGGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGC ATGAGCCACCGCGCCCGGCCTATTTTTTTATTTTTTTAAATTTTATTCTAGGTTTTAAGA GAACTACTGCTGGCCGGGCGAGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGTCCG AGAAGGGCAGATCCCCAGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACC CCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTTACGAGCGCTTGTAATCCTAG CTACCTGGGAAACTGAGGCAGGAGAATCACTTTAACCCAGGAGGCGGAGGTTGTGGTGAG CCGAGATTGCGCCATTGCACTCTAGCTTGGGCAACAAGAGCAAAACTCCATCTCAAAAAA AAAGAACTACTGCCTTGGCATATGAATTAGATATCAAAAGGGGTGATCTTTTTTTTTTTC CTGCTAACCTCATCTCCCTTTCCAGGCCTCTACTACGTGGACAGTGAAGGGAACCGGATT TCAGGGGCCACCTTCTCTGTAGGTTCTGGCTCTGTGTATGCATATGGGGTCATGGATCGG GGCTATTCCTATGACCTGGAAGTGGAGCAGGCCTATGATCTGGCCCGTCGAGCCATCTAC CAAGCCACCTACAGAGATGCCTACTCAGGAGGTGCAGTCAACCTCTACCACGTGCGGGAG GATGGCTGGATCCGAGTCTCCAGTGACAATGTGGCTGATCTACATGAGAAGTATAGTGGC TCTACCCCCTGAAAGAGGGTGGATGCAGCTGCTTGTGTTTCTTGGGGTGACTGTCATTGG TAATACGGACACAGTGACCCATCCTCCATCCTATTTATAGTGGAAGGGCCTTCAATTGTA TCAGTACTTTTTTTTAAGCTCTGGCACATTGACCTCTATGTGTTACCAGTCATTAATGAG CTGCTGCAGAGGTGACTATTTGTTTTACTTTCTTGGATGTTAACATTACACTACTCACTA CTCAATCTCA OMIM ID 600306