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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMB6 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5694 Official gene symbol PSMB6 Full name proteasome (prosome, macropain) subunit, beta type, 6 Aliases ,DELTA,LMPY,MGC5169,Y, Gene summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 1i (proteasome beta 9 subunit). [provided by RefSeq] Location Chromosome: 17   Locus: 17p13 Gene position 4699457 - 4701790  Map Viewer Gene orientation plus Gene size 2334 bp Gene sequence >PSMB6:4302831..4305164:Length=2334 ACAGTTGCTTTGAGGCAGTACCGGAGGAGAAAGATGGCGGCTACCTTACTAGCTGCTCGG GGAGCCGGGCCAGCACCGGCTTGGGGGCCGGAGGCGTTCACTCCAGACTGGGAAAGCCGA GAAGTTTCCACTGGGGTGAGGAAGGAATCGGGGTTCATAGGACGTGCACAAGGCCTGACG CGATGGGAAGATAAAGCCTGAGTGGGGTTGAGAGATCTGGCAGGGGTGGAGAGGAGGTGG AATGTGTTGTGCTCCAGGAATGGGGAGAGGTACCCCGAAGATGGTGGAGTGGTGCGGTAG CTTCGTAGTGGGAGGTGGAGGGTGGGCTGAAGTTTGAAATTCTGAAATCCTGCGAGGCTA GTGAGGATCTTGGGCTTAAGTACGGGATGAGTCTTTTGAGATTTGAGGGTTGGCATTCTG GTATTCTGCGGGGTGCTGAGGCCCCTATAAGATTTGAAAATGGTTCAGCGACGGACAGAT TTTGTATTTTTGGAACTAGGTAGAGAGATCATTGAGGTTTGTGTCTGCTGGAGAATGTAG ACTTACTCCTTTTTCCCTTTTCCCAGACCACTATCATGGCCGTGCAGTTTGACGGGGGCG TGGTTCTGGGGGCGGACTCCAGAACAACCACTGGGTGAGCTCAGGACAGATTTGTGAAAG GTCTTCCCATCTTCCTTTTCCTTTCCTGCCTGCCAGCCCACCCTGCCTGCCTCCACAGAC CACTGTGGGAAGAGAGGTTTCTTCTCTCTCTGGAGATAAAGATTTGTCCCAACTTTTGTT ACTTTCAGTTCCCCTCACTCGTTAGTGGAATCCTTACAAAAGTCTGTTCTCCAGCCCGCT TCAGTTTGGATGAGAATAAGCAATACTGGAGGCCAGGCACGGTGGCTCACGCCTGTAATC CCAGTACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCC TGGCCAACATGGCGAAACCCCGTCTCTACTAAAAAATACAAAAATTAGCCGTGCGTGGCG GTGCGTGCCTGCAGTCCCAGCTACTTGGGAGGCTAGGGCTAGAGAATCGCTTGGACCCAG GAGGTGGATGTTGCAGTGAGCAGAGATCGCGTCACTGTACTCCAGCCTGGGCAACAGAGC GAGACTCCATCTCAAAGAAAAAGGAAAAAAAGGCAATACTGGACATCCTATCCCTGAGCC CTAAGAGAGTGGGTAGTGATGGGATGGAGGTGGAAGACAGGTGGGCTCCTTTCCTCACTA TTCTGCCATCCTGCAGGTCCTACATCGCCAATCGAGTGACTGACAAGCTGACACCTATTC ACGACCGCATTTTCTGCTGTCGCTCAGGCTCAGCTGCTGATACCCAGGCAGTAGCTGATG CTGTCACCTACCAGCTCGGTTTCCACAGGTGCTTGTGGGCAGGGGAGGGGCAAGTATCTG AAGGGAGTTGGAAGCTGAGGAGCTAAATAGCCTGACTTCTAGGTCTTGAAACTTTCTCTG TGACTTCCCTGACCCTCTAGCATTGAACTGAATGAGCCTCCACTGGTCCACACAGCAGCC AGCCTCTTTAAGGAGATGTGTTACCGATACCGGGAAGACCTGATGGCGGGAATCATCATC GCAGGCTGGGACCCTCAAGAAGGAGGGCAGGTCAGATCCCCACCCGACCAGAGCACACTT GAGCCAGGACTTTTATCCTCTCCCCAGCCATTTTCTTTTTCTTTCCAGTCTCTACCTCAC TTATTCTTACTATTAACGTGCCTCAGACCAATAGCAGAATGGACAGGTGAATGTACGTGT GTTGGAGGGAGGATACGACTGGTGACTCCTCTCCTTCTATCTGGCAGGTGTACTCAGTGC CTATGGGGGGTATGATGGTAAGGCAGTCCTTTGCCATTGGAGGCTCCGGGAGCTCCTACA TCTATGGCTATGTTGATGCTACCTACCGGGAAGGCATGACCAAGGAAGAGTGTCTGCAAT TCACTGCCAATGGTGAGAGCTTAGGCTTCTGGGCCTATGAGCTTCAACCCCAACTACCCA AGCCAGGCCAGCATTCCTCATTCCTTGCAGTGATCCCGGCATCTGAATCTGAACCCAGCT TTCTTCTTTTATCCACAGCTCTCGCTTTGGCCATGGAGCGGGATGGCTCCAGTGGAGGAG TGATCCGCCTGGCAGCCATTGCAGAGTCAGGGGTAGAGCGGCAAGTACTTTTGGGAGACC AGATACCCAAATTCGCCGTTGCCACTTTACCACCCGCCTGAATCCTGGGATTCTAGTATG CAATAAGAGATGCCCTGTACTGATGCAAAATTTAATAAAGTTTGTCACAGAGAA OMIM ID 600307