Home

Search

Browse

Statistics

User guide

FAQs

Links

Questions

Contribute

Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMB10 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 5699 Official gene symbol PSMB10 Full name proteasome (prosome, macropain) subunit, beta type, 10 Aliases ,LMP10,MECL1,MGC1665,beta2i, Gene summary The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq] Location Chromosome: 16   Locus: 16q22.1 Gene position 67970753 - 67968407  Map Viewer Gene orientation minus Gene size 2347 bp Gene sequence >PSMB10:complement(21582606..21584952):Length=2347 AGACGTGAAGCCTAGCAGAGGACTTTTTAGCTGCTCACTGGCCCCGCTTGTCTGGCCGAC TCATCCGCCCGCGACCCCTAATCCCCTCTGCCTGCCCCAAGATGCTGAAGCCAGCCCTGG AGCCCCGAGGGGGCTTCTCCTTCGAGAACTGCCAAAGGTGAAGCGGGGGCGCGGGGGGCG GTCACTCCTGAGCCGCCTCTGCTTGCTCGTGGCCTTTTTTCCTGGCTGGGGGTGGGGGAG GGTGTGTTGGTCGACTTGGGTTCCAGGCTTACCCCGGAAGATGAGGGAGACGGGGACCAG GTTAGGGGAAGCAACAGGGGTCTTGAAAGCAGAGCCGAAACATGGGCGCCCTCCTCCGTT TCCAGAAATGCATCATTGGAACGCGTCCTCCCGGGGCTCAAGGTCCCTCACGCACGCAAG ACCGGGACCACCATCGCGGGCCTGGTGTTCCAAGTGAGCAGCGGGGAGGGACGGGGAGCT GGAGGGGAGCCGAGAGTATCGAGCAGGCACTGAAGCTGCGGTCCCTCCCTCTCCTCAGGA CGGGGTCATTCTGGGCGCCGATACGCGAGCCACTAACGATTCGGTCGTGGCGGACAAGAG CTGCGAGAAGATCCACTTCATCGCCCCCAAAATCTAGTGAGACTCCCGAGCCCAGTTCCC GTACGCAAAAAAGAACGGCCCCCTCGTTCCCACTCCGGTCCCCGCACGTCCCAGCCCTGC CCACACCGATCCTCCCTTTTGCCTCAGCTGCTGTGGGGCTGGAGTAGCCGCGGACGCCGA GATGACCACACGGATGGTGGCGTCCAAGATGGAGCTACACGCGTTATCTACGGGCCGCGA GCCCCGCGTGGCCACGGTCACTCGCATCCTGCGCCAGACGCTCTTCAGGTGCGGGGGCAG GGCTAACAGGACCCCGGCAGGGGTAGTTACGGGGTTGGGGCCATTGGAAGGCGGGACAGA AAGAAGGGCGGGACCGCGACGGGCCAGGTGACCGGAAGAGGCCGGCCCAAGAGAACCTGG GCTACAGGAAAAGGCGATGTCAGTCATCGGGCGCCAGCCCACAGGAAGGGGCGGGGATAG CACCTAGGAGCTGGGCATAGAGAGGTGGGGCCTAGGCCCCAGCTTGTGGCCGACCCCGCC CATCCTCGAGCAGGTACCAGGGCCACGTGGGTGCATCGCTGATCGTGGGCGGCGTAGACC TGACTGGACCGCAGCTCTACGGTGTGCATCCCCATGGCTCCTACAGCCGTCTGCCCTTCA CAGCCCTGGGTGAGCGCTTCTGTCCCTTCTCCTCGAACTCTGCCCCTGTGACCTTGGCCT CACTCCAAACGGCGTCGCAGCGGTTGACTTCAGATGCTTCTCCTGCCTTCAGGCTCTGGT CAGGACGCGGCCCTGGCGGTGCTAGAAGACCGGTTCCAGCCGAACATGACGGTGAGCGGC CTCTGTCCCCGACTTTGTGGTCGCTGGTGGGATGTGCACCCGGGAGCTGGGGGAGCACAG GACCCTGGCCCAGTGCGGGTGGCTAAGGCTTGTCGGAGGAGGTGACCACTGAAGGGTGAG TGGAGTAAGGGCAGAGAAGTGCGGTCCCGACATAACACCGTCCAATACCAAAGCCTGCAC GGCTGGGAGAAGTCGAAGCTCACAGAGGATCTTTAGGAGCCGAGGGCGGAGAGAAGGACC AGTAGGGTCCTACTTATATCAACGTCTGGAGCCTAGATTTTGTTTGGGGTGGGATGGAAG CAGGTGATGTTGCCTCAGAGGTGGCTAAGGCTCAGAGGGAGAAACACAGTGGGGGTTTGG AGGGCAAGACCAGATTGGGTAAGTGGACAGGCAAGTCCCCAGGCTGTAGCCTAAGTTAAC AGCAGAGAGAGCCCGTTAGGTCTCACACACCCATCACCGCAGCTGGAGGCTGCTCAGGGG CTGCTGGTGGAAGCCGTCACCGCCGGGATCTTGGGTGACCTGGGCTCCGGGGGCAATGTG GACGCATGTGTGATCACAAAGACTGGCGCCAAGCTGCTGCGGACACTGAGCTCACCCACA GAGCCCGTGAAGAGGTGAGAGCTGGAGATCGGGGACCACAGGGATGTGTGGGGCTATAGC AGGGGAGATAGGGGGCTGCAAAAAGGGGATGGGCCACATGACAGGCCCATGTTCAGAGGC TGTCCCTCCTCCCTCCCAGGTCTGGCCGCTACCACTTTGTGCCTGGAACCACAGCTGTCC TGACCCAGACAGTGAAGCCACTAACCCTGGAGCTAGTGGAGGAAACTGTGCAGGCTATGG AGGTGGAGTAAGCTGAGGCTTAGAGCTTGGAACAAGGGGGAATAAACCCAGAAAATACAG TTAAACA OMIM ID 176847