Entrez gene ID | | 57129 |
Official gene symbol | | MRPL47 |
Full name | | mitochondrial ribosomal protein L47 |
Aliases | | ,CGI-204,MGC45403,NCM1, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3q26.33 |
Gene position | | 179322434 - 179306253 Map Viewer |
Gene orientation | | minus |
Gene size | | 16182 bp |
Gene sequence |
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OMIM ID | | 611852 |
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