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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PSMD7 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5713
Official gene symbolPSMD7
Full nameproteasome (prosome, macropain) 26S subunit, non-ATPase, 7
Aliases,MOV34,P40,Rpn8,S12,
Gene summaryThe 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. [provided by RefSeq]
LocationChromosome: 16   Locus: 16q23-q24
Gene position74330681 - 74340186  Map Viewer
Gene orientationplus
Gene size9506 bp
Gene sequence
OMIM ID157970