Entrez gene ID | | 57132 |
Official gene symbol | | CHMP1B |
Full name | | chromatin modifying protein 1B |
Aliases | | ,C10orf2,C18-ORF2,C18orf2,CHMP1.5,Vps46-2,Vps46B, |
Gene summary | | CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM] |
Location | | Chromosome: 18 Locus: 18p11.21 |
Gene position | | 11851389 - 11854448 Map Viewer |
Gene orientation | | plus |
Gene size | | 3060 bp |
Gene sequence |
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OMIM ID | | 606486 |
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