Entrez gene ID | | 5729 |
Official gene symbol | | PTGDR |
Full name | | prostaglandin D2 receptor (DP) |
Aliases | | ,AS1,ASRT1,DP,DP1,MGC49004, |
Gene summary | | The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. [provided by RefSeq] |
Location | | Chromosome: 14 Locus: 14q22.1 |
Gene position | | 52734431 - 52743442 Map Viewer |
Gene orientation | | plus |
Gene size | | 9012 bp |
Gene sequence |
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OMIM ID | | 604687 |