Entrez gene ID | | 5731 |
Official gene symbol | | PTGER1 |
Full name | | prostaglandin E receptor 1 (subtype EP1), 42kDa |
Aliases | | ,EP1, |
Gene summary | | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.1 |
Gene position | | 14586174 - 14583278 Map Viewer |
Gene orientation | | minus |
Gene size | | 2897 bp |
Gene sequence |
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OMIM ID | | 176802 |