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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC12A5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57468
Official gene symbolSLC12A5
Full namesolute carrier family 12 (potassium/chloride transporter), member 5
Aliases,KCC2,KIAA1176,
Gene summaryK-Cl cotransporters are proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The protein encoded by this gene is an integral membrane K-Cl cotransporter that can function in either a net efflux or influx pathway, depending on the chemical concentration gradients of potassium and chloride. The encoded protein can act as a homomultimer, or as a heteromultimer with other K-Cl cotransporters, to maintain chloride homeostasis in neurons. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.12
Gene position44650329 - 44688789  Map Viewer
Gene orientationplus
Gene size38461 bp
Gene sequence
OMIM ID606726