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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for AHRR (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57491
Official gene symbolAHRR
Full namearyl-hydrocarbon receptor repressor
Aliases,AHH,AHHR,KIAA1234,MGC167813,MGC176630,bHLHe77,
Gene summaryDioxin is a teratogen that exerts its effects through the arylhydrocarbon receptor in conjunction with the receptor's binding partner, arylhydrocarbon receptor nuclear translocator. The protein encoded by this gene represses signal transduction by the arylhydrocarbon receptor by competing with the arylhydrocarbon receptor nuclear translocator for binding to the arylhydrocarbon receptor. Expression of the repressor is stimulated by the receptor/translocator heterodimer, thereby regulating receptor function through a negative feedback mechanism. In addition, the encoded protein can bind to nuclear factor kappa-B. [provided by RefSeq]
LocationChromosome: 5   Locus: 5p15.3
Gene position304291 - 438406  Map Viewer
Gene orientationplus
Gene size134116 bp
Gene sequence
OMIM ID606517