| Entrez gene ID | | 57574 |
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| Official gene symbol | | MARCH4 |
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| Full name | | membrane-associated ring finger (C3HC4) 4 |
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| Aliases | | ,MARCH-IV,MGC104908,RNF174, |
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| Gene summary | | MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM] |
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| Location | | Chromosome: 2 Locus: 2q35 |
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| Gene position | | 217236750 - 217122585 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 114166 bp |
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| Gene sequence |
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| OMIM ID | | 608208 |
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