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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PREX1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57580
Official gene symbolPREX1
Full namephosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Aliases,KIAA1415,P-REX1,
Gene summaryThe protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q13.13
Gene position47444420 - 47240793  Map Viewer
Gene orientationminus
Gene size203628 bp
Gene sequence
OMIM ID606905