Entrez gene ID | | 57580 |
Official gene symbol | | PREX1 |
Full name | | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
Aliases | | ,KIAA1415,P-REX1, |
Gene summary | | The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q13.13 |
Gene position | | 47444420 - 47240793 Map Viewer |
Gene orientation | | minus |
Gene size | | 203628 bp |
Gene sequence |
| |
OMIM ID | | 606905 |
|