Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SPTBN4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID57731
Official gene symbolSPTBN4
Full namespectrin, beta, non-erythrocytic 4
Aliases,KIAA1642,QV,SPNB4,SPTBN3,
Gene summarySpectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.13
Gene position40973126 - 41082365  Map Viewer
Gene orientationplus
Gene size109240 bp
Gene sequence
OMIM ID606214