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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPN3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5774
Official gene symbolPTPN3
Full nameprotein tyrosine phosphatase, non-receptor type 3
Aliases,DKFZp686N0569,PTPH1,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 9   Locus: 9q31
Gene position112260593 - 112137974  Map Viewer
Gene orientationminus
Gene size122620 bp
Gene sequence
OMIM ID176877