Entrez gene ID | | 5774 |
Official gene symbol | | PTPN3 |
Full name | | protein tyrosine phosphatase, non-receptor type 3 |
Aliases | | ,DKFZp686N0569,PTPH1, |
Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q31 |
Gene position | | 112260593 - 112137974 Map Viewer |
Gene orientation | | minus |
Gene size | | 122620 bp |
Gene sequence |
| |
OMIM ID | | 176877 |
|