Entrez gene ID | | 5775 |
Official gene symbol | | PTPN4 |
Full name | | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
Aliases | | ,PTPMEG,PTPMEG1, |
Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q14.2 |
Gene position | | 120517207 - 120735037 Map Viewer |
Gene orientation | | plus |
Gene size | | 217831 bp |
Gene sequence |
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OMIM ID | | 176878 |
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