Entrez gene ID | | 57761 |
Official gene symbol | | TRIB3 |
Full name | | tribbles homolog 3 (Drosophila) |
Aliases | | ,C20orf97,NIPK,SINK,SKIP3,TRB3, |
Gene summary | | The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p13-p12.2 |
Gene position | | 361308 - 378203 Map Viewer |
Gene orientation | | plus |
Gene size | | 16896 bp |
Gene sequence |
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OMIM ID | | 607898 |