Entrez gene ID | | 5784 |
Official gene symbol | | PTPN14 |
Full name | | protein tyrosine phosphatase, non-receptor type 14 |
Aliases | | ,MGC126803,PEZ,PTP36, |
Gene summary | | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q32.2 |
Gene position | | 214725024 - 214522039 Map Viewer |
Gene orientation | | minus |
Gene size | | 202986 bp |
Gene sequence |
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OMIM ID | | 603155 |
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