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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPN14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5784
Official gene symbolPTPN14
Full nameprotein tyrosine phosphatase, non-receptor type 14
Aliases,MGC126803,PEZ,PTP36,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q32.2
Gene position214725024 - 214522039  Map Viewer
Gene orientationminus
Gene size202986 bp
Gene sequence
OMIM ID603155