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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5786
Official gene symbolPTPRA
Full nameprotein tyrosine phosphatase, receptor type, A
Aliases,HEPTP,HLPR,HPTPA,HPTPalpha,LRP,PTPA,PTPRL2,R-PTP-alpha,RPTPA,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported. [provided by RefSeq]
LocationChromosome: 20   Locus: 20p13
Gene position2844841 - 3019315  Map Viewer
Gene orientationplus
Gene size174475 bp
Gene sequence
OMIM ID176884