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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRH (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5794
Official gene symbolPTPRH
Full nameprotein tyrosine phosphatase, receptor type, H
Aliases,FLJ39938,MGC133058,MGC133059,SAP1,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 19   Locus: 19q13.4
Gene position55720874 - 55692615  Map Viewer
Gene orientationminus
Gene size28260 bp
Gene sequence
OMIM ID602510