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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTPRN (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5798
Official gene symbolPTPRN
Full nameprotein tyrosine phosphatase, receptor type, N
Aliases,FLJ16131,IA-2,IA-2/PTP,IA2,ICA512,R-PTP-N,
Gene summaryThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q35-q36.1
Gene position220174143 - 220154345  Map Viewer
Gene orientationminus
Gene size19799 bp
Gene sequence
OMIM ID601773