| Entrez gene ID | | 5803 |
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| Official gene symbol | | PTPRZ1 |
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| Full name | | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
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| Aliases | | ,HPTPZ,HPTPzeta,PTP-ZETA,PTP18,PTPRZ,PTPZ,RPTPB,RPTPbeta,phosphacan, |
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| Gene summary | | This gene is a member of the receptor type protein tyrosine phosphatase family and encodes a single-pass type I membrane protein with two cytoplasmic tyrosine-protein phosphatase domains, an alpha-carbonic anhydrase domain and a fibronectin type-III domain. Expression of this gene is induced in gastric cancer cells, in the remyelinating oligodendrocytes of multiple sclerosis lesions, and in human embryonic kidney cells under hypoxic conditions. Both the protein and transcript are overexpressed in glioblastoma cells, promoting their haptotactic migration. Alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq] |
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| Location | | Chromosome: 7 Locus: 7q31.3 |
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| Gene position | | 121513159 - 121702090 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 188932 bp |
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| Gene sequence |
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| OMIM ID | | 176891 |
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