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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BAX (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 581 Official gene symbol BAX Full name BCL2-associated X protein Aliases ,BCL2L4, Gene summary The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq] Location Chromosome: 19   Locus: 19q13.3-q13.4 Gene position 49458117 - 49465055  Map Viewer Gene orientation plus Gene size 6939 bp Gene sequence >BAX:21726335..21733273:Length=6939 TCACGTGACCCGGGCGCGCTGCGGCCGCCCGCGCGGACCCGGCGAGAGGCGGCGGCGGGA GCGGCGGTGATGGACGGGTCCGGGGAGCAGCCCAGAGGCGGGGGTGAGGCGGGAGGCAGA CGGGCGGGAGGAGGGCGAGCCCCCTCGCCGGCCCGTCCGGGATCCTTCCTACCGGCCTGG GGCTGTGCGATCTCCAAGCACTGAGGGGCAGAAACTCCCGGATCGGGCGCTGCCAGCCTC CAGTCCCCTCCGTCCTCGGAGGTTCCTGGCTCTCTGATCCCCGTGTCCCGATCCCTGCCT CTCTGGCGCTCTCGGACCCTCGAGAACCAGGGGATCTCGGAAGCCAAGCCCCCGGGCAGG CCCGGGCTTGTCGCCCGCACCACTTCCTGCCTCTGGCACTGGTGGGAGGGGCGGGTCTCG CCTCTGCCCCCTCAGGCCAGGGGTCTGGATGCATATAGCGTTCCCCTAGCCTCTTTCCCC GGGGAGAATGTAGGATACAGGCCCAGCCTCCTGGCCTTTCTCCATCAGGGACTCAGTTGT CTGGGCCCCCCCGTCACTTTATCTGCTAGGGTCCCAGAAGTCCAGGGTCCCCAGCTCTGT CCTCCCTCAGGGGCCGTGAGTCTCCACAGTCTCCTGATCCCCTAGAACCCAAGAGTCCAG GTACCTCTTCCCTTCCTTTCTCCTCTAGGGCCCACCAGCTCTGAGCAGATCATGAAGACA GGGGCCCTTTTGCTTCAGGGGTGAGTTTGAGGTCTGATTATTGTGGCACAGATTTGAGGA GTGACACCCCGTTCTGATTCTGCACCCTCACTCCATCCCCACTCTAGTTTCATCCAGGAT CGAGCAGGGCGAATGGGGGGGGAGGCACCCGAGCTGGCCCTGGACCCGGTGCCTCAGGAT GCGTCCACCAAGAAGCTGAGCGAGTGTCTCAAGCGCATCGGGGACGAACTGGACAGTAAC ATGGAGCTGCAGAGGTGTGGGCCCCTGAGGACCCAGAAGTCCAGCCACTGGGCTCCTTCA GGACACAGGACTCTCAGCCCCGCATTCTCCTCCTCCCCTAAGAACTAGGAGTCTGGGCCC CACAACTCAGCGCAAACATTCCGGACTCCCAGCCCTCCTCTCTGCCAGGATCTTAAAACC CTCCTTCAGGGAGTCATTTTTCCCACCTTCCTAAATGTCTGTCTTGTCCCCTTCCCTTGT CCCCCGTTGGCCTGTTGCTTTTCATTTCAGCCTGGCTTGGGGCTCAGTCTCCTTATCTTT AGTGTGCGGTGGATGCGGGAATTTTCCACCATCAGCCTGATGCCTGCTCCCCGGCACTGG TTCTCCTCTCTCCTGCAGGATGATTGCCGCCGTGGACACAGACTCCCCCCGAGAGGTCTT TTTCCGAGTGGCAGCTGACATGTTTTCTGACGGCAACTTCAACTGGGGCCGGGTTGTCGC CCTTTTCTACTTTGCCAGCAAACTGGTGCTCAAGGTGGGCAGCTGCAGGGCAGTGAGCCC AGGGATGCTCCCCCTCAGATCTGTGAGGACCTGGGGATCGTGGTATCAACCCCCTGCAGT GGCCCAGTGACCACAGAGGGCATGGAGAGAGATGGCTGTGCACTGGGTGTCTGCTCCTTC TTTTATTCATTCAACAAGCATTTACTGGACCTGCTATGTGCCAGGCCTATACCTGGCACC TGGGACACAGCACTGTACAAAGCAGGCTACATCCCTGCTCTCAGGGAGTTCACGTGCAGG GGTGAAGTAAAGTGGGCAGTGTGATTTAGCAGAGTGGTCAGGAAAGATTTCTATTTTTTT TTTTTTTTTTTTTGAGATGGAGTTTTGCTCTTGTTGCCCAGGCTTGAGTGCAATGGCATG ATCTTGGTTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCTTCC TGAGTAGCTGGGATTATGGGTGTGCACCATTATCCCTGGCTTTTTTTTTTTTTTTTTTTT TTTTTGTATTTTTAGTAGAGACGGGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCT GACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCA CCGCAACAAGCCAGGAAAGACTTCTAAGGGCAGGTGACATCAAAGAGCAGGTGACATTAA AGCCAAAGCTAGAATGATAAGAAGCATGCAGTGATCTATAGTGATCGGGGGGAAGAGGCA TCTGGTAGAGGGAACAGCAAGTGCAAAGGCCCTGAGGTAGGACCAAGCCTCATCTTTTGA CAGTAGGGAGGAGGCCAGTGCTGTTGGAACAGAGTGAACTGGGGAGAGGGTGGGAAAGGA AGGCACAGTTGGGCAGGGGCAGATTGTGTGGAGTTTTTCGGGCTGCTGGAAAGACTTTTT CTTTTCTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTTTGTTGCCCAG GCTGGAGTGCAATGGCGCCATCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGA CTCTCATGCTTTAGCCTCCCAAGTAGCTAGAATTACAGGCACACACCACCATGCCTGGCT AGTTTTTGTATTTTTAGTAGAGACGGAGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACT CCTGGCCTCAAGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAA CCACTGCACCCAGCCTGGAAAGACTTTAACTTTACTCTGAGTGTGATGGGAGTGATTGGC TGGTTTTAAATACGGAAGCGACAAGACCTGATTTATAACTTTAAGAGATTATTCTAGCAA GTATAGATGCCCCTTGACTTGCAATGGTGTTACATCCTAGTAATCCCATCATAAATTGAA AATAACATAAGTTGAAAATGCATTCAATGCCCCGATAAACCCATAGTAAGGTCAAAATTG TAAGTCAAACCGTCATAAGTTGGGGACTGTCTGTATAGCAAAATGTTAATTGTAGAATCT AATTATAGGTGGCGGCTATATGGCTTTTAACTGTGAAATTCTTTTAACTTTTCATTATGA AGATTCTCATAAGAAAATGTGGTGGGGGTGGTGGTGAAATGCTCCTGGCTGTTGTTGGCC AAAAGAGATCATGAGGCACAAGGGCAGAAGCGAGGATCCTGGAGAGGTGGCACCTGTCAT AGTCTTGCTGAAAGATGACAAGCCCTGGTGGTAGCAGCAGAGGTGCGGGGGGGGCATTTT TTTTTTTAAGAGGTAGGGTCTTGCTCTGTTGGCCAGGCTGGAGTGCAGTAGTGATCATAG CTCACTGCAGCCTCAAACCGCTGGGGTCAAGCAGTTCTCTCGCCTCAGTCTCCAGAGTAG CTGAGACTACAGGAGCATGCCACCACGCCCCACTAACTGTTGCATTAGTCTTTTTCTATA GAGACGGGGTCTCGCTATGTTGTCCAGGCTGGTCTCCAACAGGGAGGGATATTTCTTTTT GGAAGATTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGGGTCTCGCTCTGTTACCAAG GCTGGAATGCAGTGGCATGACCTTGGCTCACTGCAGTCTCCACCTCCTGGGTTCAAGCAA TTCTACCTCAGCCTCCTGAGAAGCTGGGATTACAGGCTCTCCCCACCACACCAGCAAATG GGAGGGATATTTCTTTCTTTCTTTCTTTTTTTTTTTTCCTGAGACGGAGTCTCTCTCGGT TGCACCCAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCACCTCCTGGG TTTAAGCGATTCTCTTGCCTCAGTCTCCCGAGTAGCTTGGGATTACAGGCGTCCGCCACC ACACCCAGCTAATTTTTGCATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTG GTCTCGAACTCCTTACCTCAGGTGATCCGCCTGCCTCGGTCTCCCAAAGTGCTGGGATTA CAGGCGTGAGCCACCGTGCTCAGCTGAGAGGGATATTTCTTGATGTGTTTTCAAGATTGA GCTGATGGGGCCTGAACGTCCGAGATGAGGGGAATAGCAGTGCAGGTGATGGTGGCACCA CCTACAGAGCGGGGATGATAGAATAGAAGTGGCCAGATAAAGGCTGCAGGAGAAGTCTTG GGAGTTGGGAGAGCAGGTCGGGGTCCATGGTCAGGGGTTGATCTTCTCTGGTCCAGAAAA GTCCTCTCTGGCTGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAG GCAGGGGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCCGT CTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGTGGGCACTTGTAGTCCCAGCTA CTCGGGAGGCTGAGGCAGAAGAATGGCGTGAACTGGGAGGCGGAGTTTGCAGTGAGCTGA GATTGCACCACTGCACTCCAGCCTGGAGCGACAGAGTGAGACTCCGTCTCAAAAAAAAAA AAAAAAAAAAAAGAAAAGTCCTCTCTGGGGAAGTGACATTTGCCCTGAGAGCTGAAGGGT AAGAATTTGCTTCGTCGAGGCCTGTTTAGGCGGAAACAGGAGTACATGAAGAAGTCCCGA GGCAGGAAGAATTTGATGGGAATTTAAAAAATTAAAAAAAAAAAAAAAAATGGGGCTGGG CATGGTGGCTCACACCTGTAATCCCGGCACTTTGGGAGGCTGAGGCATGCGGATCACCTA AGGCCAGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCTTGTCTGCACTAAAAATT CAAAAAAAAAAAAAAAAATAGCCCGGTGTGGTGGCGGATGCCTGTAATACCAGCTGCTTA GGAGGCTCAGGCAGGAGGATCACTTAAATCTGGGAGGCGGAGGTTGCAATGAGCCGAGAC TGCACTATTGTACTCCAGCCTGGGCAACAAGATCAAAACTCTATCTCAAAAAAAAAAAAA AAAATTAGCCAGGCATGTTGGCAGGCACCTGTAATCCCAACCCTTTGGGAGGCTGGGGCA GGAGAATTGCTTGAACCCAGAAGGCAAAGCTTTCAGTGAGCCGAGATTGCGCCACTGCAC TCCATCCTGGGTGTCAGAGCAAGACTCCATCTTAAAAAAAAAAAATGGAAGCAGCTCAGC GAGGCACAAAACAGGAAGTGGAAAGGTGGAGTGAGGTCAGGCCAAAGCCTGCACACAGGG CTTGTGGGCTGCACTGTGCCTTCGGGTCTTCATCCTGAGGGTACTGGGGAGCCACAGAAG GCTCAGGGGTGGGGCAGTTGAGAGTAACATTATCTTGTTTACAATTTTATTTTTTTTATT TATTTATTTTTTGAGACGGATTCTTGCTCTATTGTCCAGGCTGGCGTGAAATGGCGTGAT CTGGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCGATTCACCTGCCTCAGCATCCCA AGGAGCTGGGATTACAGGTGCCTGCCACCACACCCAGCTAATTTTTGTATTTATTTATTT TGAGATGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCAACCTCGGCTCAC TGCAACCTCCGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGACTCCCAAGTAGCTGGG ATTACAGGCATGTGCCACCACGCCCGGCTAATTTTGTATTTTTAGTAGAGATGGCATTAC TCCGTATTGGTCAGGCTGGTCTTGAACTCCCGACCTCAAGTGATCCGCCTGCCTTGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGCCGCCGCACCTGGCCATGTTTACAATTTTTGA AGCCGACTTCAATTGTGGGTGGCAGAAATCTTTGAGGGGAGGCAAAGAATTGACAAAGGA GGTTTGGGGCCACTATCTCCAGGCAGTGGGGACAAGGTTCAGTCCCTAACGCCCACTCCA CTCCCCACAGGCCCTGTGCACCAAGGTGCCGGAACTGATCAGAACCATCATGGGCTGGAC ATTGGACTTCCTCCGGGAGCGGCTGTTGGGCTGGATCCAAGACCAGGGTGGTTGGGTGAG ACTCCTCAAGCCTCCTCACCCCCACCACCGCGCCCTCACCACCGCCCCTGCCCCACCGTC CCTGCCCCCCGCCACTCCTCTGGGACCCTGGGCCTTCTGGAGCAGGTCACAGTGGTGCCC TCTCCCCATCTTCAGATCATCAGATGTGGTCTATAATGCGTTTTCCTTACGTGTCTGATC AATCCCCGATTCATCTACCCTGCTGACCTCCCAGTGACCCCTGACCTCACTGTGACCTTG ACTTGATTAGTGCCTTCTGCCCTCCCTGGAGCCTCCACTGCCTCTGGAATTGCTCAAGTT CATTGATGACCCTCTGACCCTAGCTCTTTCCTTTTTTTTTTTTTCCCCACTGAGAAGGGG TCTCGCTATGTTGCCCAGGTTGGTCTCGAACTCCTGGCCTCAAGCGATCCTCCCGCCTCA GCCTCTCAAAGTGCTGGGATTACAGGTGTGAGCCACCATGCCTGGCCTGAGTCCAGCTCT TTAATGCCCGTTCATCTCAGTCCCCTGCCCGCAATCCTGCCTTCTGGCCTCCTCCGTCCC TGATCCCGCCTCTGCCTGCCCAGGGGCTGCCCCTGGCCGAGTCACTGAAGCGACTGATGT CCCTGTCTCCAGGACGGCCTCCTCTCCTACTTTGGGACGCCCACGTGGCAGACCGTGACC ATCTTTGTGGCGGGAGTGCTCACCGCCTCACTCACCATCTGGAAGAAGATGGGCTGAGGC CCCCAGCTGCCTTGGACTGTGTTTTTCCTCCATAAATTATGGCATTTTTCTGGGAGGGGT GGGGATTGGGGGACGTGGGCATTTTTCTTACTTTTGTAATTATTGGGGGGTGTGGGGAAG AGTGGTCTTGAGGGGGTAATAAACCTCCTTCGGGACACA OMIM ID 600040