| Entrez gene ID | | 58187 |
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| Official gene symbol | | Cldn10a |
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| Full name | | claudin 10A |
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| Aliases | | 6720456I16Rik,Cldn10,Cldn10b,D14Ertd728e |
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| Gene summary | | This intronless gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight unction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Six alternatively spliced transcript variants have been identified, which encode different isoforms with distinct electric charge of the first extracellular loop and with or without the fourth transmembrane region. These isoforms exhibit distinct localization and function in paracellular anion or cation permeability. [provided by RefSeq] |
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| Location | | Chromosome: 14 Locus: 14 E4 |
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| Gene position | | 119187093 - 119273747 Map Viewer |
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| Gene orientation | | plus |
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| Gene size | | 86655 bp |
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| Gene sequence |
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