Entrez gene ID | | 58494 |
Official gene symbol | | JAM2 |
Full name | | junctional adhesion molecule 2 |
Aliases | | ,C21orf43,CD322,JAM-B,JAMB,PRO245,VE-JAM,VEJAM, |
Gene summary | | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq] |
Location | | Chromosome: 21 Locus: 21q21.2 |
Gene position | | 27011589 - 27087235 Map Viewer |
Gene orientation | | plus |
Gene size | | 75647 bp |
Gene sequence |
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OMIM ID | | 606870 |