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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for JAM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID58494
Official gene symbolJAM2
Full namejunctional adhesion molecule 2
Aliases,C21orf43,CD322,JAM-B,JAMB,PRO245,VE-JAM,VEJAM,
Gene summaryTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq]
LocationChromosome: 21   Locus: 21q21.2
Gene position27011589 - 27087235  Map Viewer
Gene orientationplus
Gene size75647 bp
Gene sequence
OMIM ID606870