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Gene information for DNASE2B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID58511
Official gene symbolDNASE2B
Full namedeoxyribonuclease II beta
Aliases,DLAD,
Gene summaryThe protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p22.3
Gene position84864215 - 84880691  Map Viewer
Gene orientationplus
Gene size16477 bp
Gene sequence
OMIM ID608057