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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SNX6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID58533
Official gene symbolSNX6
Full namesorting nexin 6
Aliases,MGC3157,MSTP010,TFAF2,
Gene summaryThis gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q13.1
Gene position35099366 - 35030618  Map Viewer
Gene orientationminus
Gene size68749 bp
Gene sequence
OMIM ID606098