Entrez gene ID | | 5859 |
Official gene symbol | | QARS |
Full name | | glutaminyl-tRNA synthetase |
Aliases | | ,GLNRS,PRO2195, |
Gene summary | | Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq] |
Location | | Chromosome: 3 Locus: 3p21.3-p21.1 |
Gene position | | 49142171 - 49133365 Map Viewer |
Gene orientation | | minus |
Gene size | | 8807 bp |
Gene sequence |
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OMIM ID | | 603727 |
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