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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for QARS (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5859
Official gene symbolQARS
Full nameglutaminyl-tRNA synthetase
Aliases,GLNRS,PRO2195,
Gene summaryAminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p21.3-p21.1
Gene position49142171 - 49133365  Map Viewer
Gene orientationminus
Gene size8807 bp
Gene sequence
OMIM ID603727