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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAP4K2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5871
Official gene symbolMAP4K2
Full namemitogen-activated protein kinase kinase kinase kinase 2
Aliases,BL44,GCK,RAB8IP,
Gene summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13
Gene position64570713 - 64556609  Map Viewer
Gene orientationminus
Gene size14105 bp
Gene sequence
OMIM ID603166