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Gene information for Txnrd1 (Rattus norvegicus)
(Information is obtained from NCBI Gene database)
Entrez gene ID58819
Official gene symbolTxnrd1
Full namethioredoxin reductase 1
AliasesMGC93353,Tr
Gene summaryThis gene encodes a member of the family of pyridine nucleotide-disulfide oxidoreductases. This protein is a flavoenzyme, which uses NADPH for reduction of thioredoxins as well as other protein and nonprotein substrates, and plays a role in protection against oxidative stress. It contains a selenocysteine (Sec) residue, which is essential for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q13
Gene position23055543 - 23093814  Map Viewer
Gene orientationminus
Gene size38272 bp
Gene sequence