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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RAD51B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5890
Official gene symbolRAD51B
Full nameRAD51-like 1 (S. cerevisiae)
Aliases,R51H2,RAD51L1,REC2,
Gene summaryThe protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q23-q24.2
Gene position68286496 - 69062738  Map Viewer
Gene orientationplus
Gene size776243 bp
Gene sequence
OMIM ID602948