| Entrez gene ID | | 59095 |
|
| Official gene symbol | | Fxyd6 |
|
| Full name | | FXYD domain-containing ion transport regulator 6 |
|
| Aliases | | 0610030I18Rik,Php |
|
| Gene summary | | This reference sequence was derived from multiple replicate ESTs and validated by similar human genomic sequence. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. This gene product, Fxyd6, is novel and has not been characterized as a protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D., sweadner@helix.mgh.harvard.edu.] |
|
| Location | | Chromosome: 9 Locus: 9 A5.2 |
|
| Gene position | | 45178268 - 45204242 Map Viewer |
|
| Gene orientation | | plus |
|
| Gene size | | 25975 bp |
|
| Gene sequence |
| |
|
|
