Entrez gene ID | | 59272 |
Official gene symbol | | ACE2 |
Full name | | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
Aliases | | ,ACEH,DKFZp434A014, |
Gene summary | | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xp22 |
Gene position | | 15620192 - 15579156 Map Viewer |
Gene orientation | | minus |
Gene size | | 41037 bp |
Gene sequence |
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OMIM ID | | 300335 |
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