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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RBBP8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5932
Official gene symbolRBBP8
Full nameretinoblastoma binding protein 8
Aliases,CTIP,RIM,
Gene summaryThe protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq]
LocationChromosome: 18   Locus: 18q11.2
Gene position20513295 - 20606449  Map Viewer
Gene orientationplus
Gene size93155 bp
Gene sequence
OMIM ID604124