Entrez gene ID | | 5954 |
Official gene symbol | | RCN1 |
Full name | | reticulocalbin 1, EF-hand calcium binding domain |
Aliases | | ,FLJ37041,PIG20,RCAL,RCN, |
Gene summary | | Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane. |
Location | | Chromosome: 11 Locus: 11p13 |
Gene position | | 32112477 - 32127272 Map Viewer |
Gene orientation | | plus |
Gene size | | 14796 bp |
Gene sequence |
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OMIM ID | | 602735 |