Entrez gene ID | | 5966 |
Official gene symbol | | REL |
Full name | | v-rel reticuloendotheliosis viral oncogene homolog (avian) |
Aliases | | ,C-Rel, |
Gene summary | | The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM] |
Location | | Chromosome: 2 Locus: 2p13-p12 |
Gene position | | 61108752 - 61150178 Map Viewer |
Gene orientation | | plus |
Gene size | | 41427 bp |
Gene sequence |
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OMIM ID | | 164910 |
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