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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BCL2A1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 597 Official gene symbol BCL2A1 Full name BCL2-related protein A1 Aliases ,ACC-1,ACC-2,BCL2L5,BFL1,GRS,HBPA1, Gene summary This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 15   Locus: 15q24.3 Gene position 80263643 - 80253232  Map Viewer Gene orientation minus Gene size 10412 bp Gene sequence >BCL2A1:complement(51043789..51054200):Length=10412 AGCCTACGCACGAAAGTGACTAGGAGGAAGGATATTATAAAGTGATGCAAACAGAAATTC CACCAGCCTCCATGTATCATCATGTGTCATAACTCAGTCAAGCTCAGTGAGCATTCTCAG CACATTGCCTCAACAGCTTCAAGGTGAGCCAGCTCAAGACTTTGCTCTCCACCAGGCAGA AGATGACAGACTGTGAATTTGGATATATTTACAGGCTGGCTCAGGACTATCTGCAGTGCG TCCTACAGATACCACAACCTGGATCAGGTCCAAGCAAAACGTCCAGAGTGCTACAAAATG TTGCGTTCTCAGTCCAAAAAGAAGTGGAAAAGAATCTGAAGTCATGCTTGGACAATGTTA ATGTTGTGTCCGTAGACACTGCCAGAACACTATTCAACCAAGTGATGGAAAAGGAGTTTG AAGACGGCATCATTAACTGGGGAAGAATTGTAACCATATTTGCATTTGAAGGTATTCTCA TCAAGAAACTTCTACGACAGCAAATTGCCCCGGATGTGGATACCTATAAGGAGATTTCAT ATTTTGTTGCGGAGTTCATAATGAATAACACAGGAGAATGGATAAGGCAAAACGGAGGCT GGGTATGTGTGATGGAAAAATTCTTCATTGTTCTTTCCTGTGAAATAGAAATTGAGAATT TCCTTGCTAGTTAAAACAACAACAAAACACTTTACCTAAGAATACTATTTTCCTTGGGTG GTTTGTTTTAATTTTTAAAATAAAAATATACTTTCTGGCTTATTTCCAATGAATCCTTGA ACTTGAACTTTATAGTTGGAAAGCACTTATGTTTTCAGTTTTTATTCTTAACAGTATAAA TTACAGTAGTGAGCTTTGGGGATTAATAAAGCACCTCTCTCATGCAGCTTCACAATCAGC TGTGCACACACTCTAATCTAGTACTTAGCTTTTGCTAGGGTTGTCATGACAGTACAGACA GTACAGAAATTTCTACAATCAGCACAGAAAGTTGCTATCAGATGCTGTTATTTTTAGGTA TTTATGGGTTGCAAAAGACAGGTGTAAATTTTTGTAAGTTCATCGCTTACAAATTGGTGT TTTTCAGTTTACTAATACATAATAAATAGTAACATATATTAATATATAGCAAATTACATT ACATATAATATATAACACATTATTACTAATAATAAATTCCGGGCTGTTAAAGTTTGTTGA TTAAAACATAATATACTGTATGACCAGCAAGAACCTTTATTCAAGAATTTTCAAATAAAA ATTTACTTTATTATCAGTGCCTAAAAAAGCCAAGACTATGTAGAGGCCTGTGTTGAAACT CATGTTGGTAAAAAGCCTGACACAGCTGGATGTATATGGTTTCCTTTATATTCCAATATA CTTAATAATTATTTTTTTAAAGCACTTAAGTGTTCATTGATCCTCTCTCCAACGGCCTTC ACCTCTCCCAAGAGGTAACCACTGTTATCAATTATTTTGCATGCAAAACATGCCTACTGA ATCTATCCATAGAAAATAAACAATACTTCTTTGTAAAACATTTTTTGTAAAAAAAGTTTT ATATAAAATGTATATGTATGCTTATGTATATGTTTTACATAACATATATGTTATACCATA TAACACATACCTTTTTTACATATACACATAGATTTTTTATGTATACATATAAATTTTGCA TACATATTTTTACATGTGTATATGTAAAAATAGTACATGGTACTAATGCTGCCACTTATT TTTTTACCCAGAATTATTTAAAATAGTATTATTAAGAGTGCTGTGTATATTCTGTTATAT GTAAGTGCTGTAGAGTACCTGGCCATTTCTAGCTGATAGCTGTTTAGGTTATTTCGAGTT TGCTGTCACACACAATGCTTCATTGAATATCATTTTACGTAAATCTTCCCTTGTGCGTGT GTGTAGTTTTCTAGGGTGGATGTTGGGTTGTAGATGCTGGGTCATGGTGTACATACATTT TTTAATTTGTTAGGTCCTTGCCCTCCAAAGTGGCTCTACCAAGTTACACTCCCATCAGCA GCTCGTTAGGATATGCCCCGGGATTCTCCTACCCCAGCTGACTAACAGTAGGTTGCTGCA ATTCATCATAATTTTCTTAATTTGTTGGGCTAAAAATATAGAGTTTATCTTGTTTCAATT CTTGTTTTCTTGATTTCTAGTAAGGTTAATTTTTTTTTTACATTTTGAGCATCTTTTCAT ATATTAACTGATCATTTGTAAATGCAGGGAATTGTCTGTTTACACCCTTTGCCCATTTTC CTTTTATTTTGTCTTTTTCTTATTGATTTGTAGGAATTCTTTGAATATTCTGGATACAAA TTATTATTTTTATTATTGTTTAAATTTTTTGAGACAGAGTTTTCATTCTTGTTGCCCAGG CTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCTGGTTTCGAGCAAT TCTCCTGCCTCATCCTCCCAAGTAGCTGGGATTACAGGCATGTGCCACCACACCCAGCTA ATTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGTCAGGCTGGTCTCGAACTCC TGACCTCGGGTGATCCTCCCCCTTTGGCCTCCCAAAGTGATGGGATCACAGGCGTGAGCC ATGCACCCAAATTATTTTTATGTATGTGGCAGATATCTTTTAGTTTGCTGATTAACGCTA ATGATGTCTTTGGTCATTATAAATGTTTAAAAGTTTGTTGCAATCAAATTTATTGATCTT TTACTTGATGCCTTTTTCATTTTGTTTAAGGCCTTCCTGCATGATAGAGCTTACTGCAGC TACTCCCCTTTCTCAATCACCTTCTTCCTGGAACTTAGTTCTTTCTAACTGAGCCTGACT GAGGCTGGGCGAATCATGTGAAATGTTTTGTCATGTTTTCTTCCGGTTGGCTGTGGGAGG CTATACTTGAGGACTGGTGGAAATTCAGCTGCACTGTGTAGATTTCAGGTGAAGGCAAAT GTTCTCTGGCACAGAGGACCACAGATGAGCCTGCAGAGAAATACTCTACTAGTTTGCAGG CTCTATTTGGGTTTGGATTGTATTTCCAACGCTTAGCATAATACTTGGAGCACACAGACA GTGAATAAATGTTAGTTAAAAATTTAACTTCTCCACAATAAATTTTGTGAGCTCCTGGAA CTCACTGTTAGCAAGAGGTGTGGAATTGTCTCTGAGAATTTCTAGTAGTACCCTCATCTT TCAAGGGTGGTACAGATGTAAACATGAGTGTGGCCGGATGAACCTCTCCCGAGTGTAGAT ACAAATACACACATTGCCTGCACGTGCACACACTCAGCCTTTCTAAAGTTTCCAAGCTCT TTTTTTTTTTTAAAAAAAACACCTGAATAGTTCAAGTTGTAGACATGAAATAAATACTCT TGGAAATGTCATTTCAAAGCAATCTCCATGCCGCTTTCCCAGCTCAGATGAGACATTGAT TCTGTCAACGATAGGCAGTGCTTTTTTGAGTCAGTGCAAACTGGCATGGAAAACTGTTAT CATCTTTTCATAGTGATGTTGACAAATCTGCTTAAATGAATGAATTTACTCTTGAATGAT TCATTTCAGGGGAAATGGCACAATCACACACCTATGCTGGTAGAGTCAGTGGCCCACAAG AAGAGGTAAGAGTAGAGAAGGCACTTACAGCTTTATCAAGATGTGAGCACATACAATCTA TAATTTAATTAAATGTTAAAATTGCCCAGAGACTTTATGAAAACTTTGAATCAACAATGC GGTATGTGCCGGGTGCAGTGGCTCATGCCTGTAATCCCAGCGCTTTGGGAGGCTGAGGTG GGTGGATTACCTGAGGTCAGGAGTTCAAGAGCAGCCTAGCTAAGATGGTAAAGCCCTGTC TCTACTGAAAATACAAAATTAGCAGGGCCTGGTGGCGGATGCCTATAATCCCAGCTACTT AGGAGGCTAAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCGGGA TTGTGCCACTCCAGCCTGGGCAACAGAGTGACTCCATCTCAAAAAAAAAAAAAAAAAAAA GCGGTATGTGAGCACAGCATAGATGTTCAGAGCACCAACTCAGAATCAGACAGACCTGGC TTCATTTCTGGGCTCGAGTGCTTACTACCTGTGTGAATTGTACAAGTTGCTTAACTTCCC TACGTCTTGTTTCCTCATCTGTAAAAACAGGAAAATATTGCAACCTATGTCCTGGGACTG GTATAAGGATCAAATTAGTTAATATATGCAAAGCACTTGAAACAATTCCTGAAAATGAGT ACTCAATACAAGTTTAGGATTTTTGTTTACCATGTAAAACAGATCCCCTAATGGGAAGAA ACGAGACTGGTCTATCAGTAATAGGACTCATAATCTCTTTCGTTATTCTCTTTCTCCTTT TTGTCAGTTGTCTTTCCTTCCTTCCTGCCTTCCTGCCTTCCTGCTTTCCTGCCTTCCTGC CTTCTTTTGTTTGTGGCTTCTCATCTCTCTTTTTGTCCTCTTCCATATTTACCATGGTTT CCTCCTGTCCGCTCTCCTAATTGGAAGTGCTGAGAGGATGTGCTCTCACAAGATCTGACA GGAGAGCTAGTGCCATTTGGCTGCCTCCAGCATTCATAAGGAAAGGATGGTTCTTAAAAA CCATTAGAATGTTCATGAGATGAAACTCATGTCTCTTCTCTTGGGATCACCCTTCCTTTT GAACCAGATGGGTCTTCTTACTTCCTCCCCCTTCAATGAAGCATTCTCCTCTGCATATGC TGGGGGAGTAGAAAGAATGCTTGGCACTCAGCTCCACATGGGAGAAATTGTGTCTACTTA ATGCATCACTGTGTACCTCATGCCTAGCATAGAAGGTAACAATATTTGCTGATGGGATGA TTCAACGAACCAACACTGAAACTGAATATTTGAACTCTGGTTTTCTCACTCACTAGAGGT ATAACCTTGGGTAAATTACTGAGGTACTCTGAGACTCAGATTCCTTATATAATGTATATA ATAATATGACATGACATATGATAATTTATTATATATGTAATATTTAATGAAAACAATCTT ACCTACCTTTAAAGGAAAGCTAAAGGATTATAAAACACTTTTTGTAAAACAGTGCTTTCC AAGCTGTCAAATACTGTGCAACTACGAGAGTCGTGGGAAATTCCAGGAAGTTTAGATAGG TAATTCTTTGCCCTTCTGAAGTAGGATGTACAGTCAGAGTTGGTGCTTTCCCAGTAACCA CCATTTTAAAGGTTGGGTCATACAGTTAGGTCAAGAGGTTTTTTTTCTTTTTTTTTTTTT TCTTTGTCATCCTCTTACTCTAAATAATAGTCCGGTCAATTTGAGGCCAAATAAATGGGC ACACAGAGACATGTATAGATGATTAACTAAGTGTTCACTTTGGCAAAGGCATTTCCAAAA GGTATAAAGATCTAGCAGCAAGGTGATACTATCTCAAGTGTTCATATATATCCTTTGATT AAATAAGTTTTGGGGCAAAATTTTCTATGTCTTTTGAATTTTTACTTGAGACTCTAAAAT CATTTAGTGAAAAATAAAAGACCCTCAAGTCAGGCAGAAATGTATGACACTTAAGTGCTA GTTCTCTAACCTTGGGAGTCAGCCTGGACTCCTGTCTCTCATAGCCCACATCCATCCATC AGCAAATCCCCCTGGCTGCCCCTTTGAAATGCTGTAATACCCTGTGCATCTAGGCCGCCT TCCTCTCTCACTTGACTCTGTCAGTAGCCTCCTGCCAGACTCCATGGTTCCATCCTTTAT CTGCTAGAATTTGTTTTCCACATAGCCCCCACAGCGATATTTTTAAAACTTGAGGGGCCG GGCGCATTGGCTCAAGTCTGTATTCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACG AGGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAATA CAAAAAATTAGCTGGGCGTGGTGGCGCATGCCTGTAATCCCAGCTACTTGGTAGGCTGAG GCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGGTGAGATCGTGCCACTG CACTCCAGCCTGGGTAACAGAGTGAGACTCTGTCTCAAAAAAATAAAATAAAATAAAAAC TTGAATTAGATCATGTCTTGGCCTAATCATAACCCTCCAAGCTGCCCTTTTACCCTGGGA ACAAAAGCACAAAATCCTGACTGTGGTCCTCAAAGCCCTACATGACCTAGCCTCTAACCG CCTCTCAAATCTCATCTGTGAATCCCTCCGTGCTCTCATAGCTCCAGCCTCCTTGGATAA GCTAAGCACATTCCACCCTCAAGGCCTTTGCACTTGCTGCTCCCTCTGCCTGGAATAATT TTCCGCCAGAAGTTTGCCTGGCTTACTTCTTCCCTTTGCTCAGGCCTCTGTTCCAAGGTT GCCTCCTCAGAGAAGTCTTCCTTGATCACCCCAACTGAGAAAGTACTACTGCCACTCTCT GTCTCCCTACCCAACTTTATTGCCTTCATAATAGTTTTCATGACTGGACATCCCATTGCA TATTTACTTGCTTATCTGTTTATTGTCTGTGTCTGCCGTGAAAATGTAAGCTTAGTGAGG GCAGGGATCCTGTATGCTTTCTTCACCACTGTGTTTCCAGTGCTTTAAATGGTACCTGGC ATGTGGCCAATGCTCAATGAATATTTCCTGAATGAATAAATGAATAATAATGTTTAGAGA AGTGGGAGTAACATAATGGTGTTTGCGTGTATTTTGTTTGTTTGTTTGTTTTTTTGAAAC AGGGTCTTGCTGTCACCCAGGCTGGAGTGCAGTGGCGCAATCTTGGCTAACTGCAGCCTC GACCTCCAGGGCTCAAGCAATCCTCCCATCTCAGCCTCCCAAAGTGCTAGGATTACAGGC TTGAGTCACTGCGCCCGGCTGCCTGTATCTTTAAAAATTCTGAGATTTTGATTTTCTTTG GACTATTGATACTGTATATTATTTTATGCTTTAGGTTTTCTTGTAACCAAGGTAGCTGAA TTTAACAAACTATCACCATTCCCAGAAATAATAAGGCCTGAACTATTCTTATTTACTACT ACATTACTGATAGGATATTGAATCCTTGTTTGTATATTTATTTTTATATAATGGTTTTAA GATACAAATAGCATCATTAAAGAAAATATATTTGAAAATAACATTTTTGAAAGGAAGAAA AGTCACTCCCATCACCCTAACATATCCACATGCAGACATTGTATGCAATTATAATTAGGG TGCACAAGAGTTTTTTCCTGTGACATATTGTAGATATTTTCAACACTGTCTCACATATTT CATGTTAACATTAGGCATTAATTTCTAATGTCTACAGAATATTTCATTAATTTGTTATAT CATAATTTACTTAACCAATTCCCAATTGTTAGACAATTTGGTTTTTTCGAGTTTTCCCCT TTTAGATATAATGCTTCAATACTGAAGCATGGGTATGCTTTTCTGGTGCCCCCTACCCTC CAATATTTTAGAAGACTGCCTCATGATAAATTTCTAACACTGGAATGACTGGTTCATAAG ATGTGTGTATAATTACAATACTCTAGCATATTGGAAAACATATTTTCTTTCCAAAAGTAT TATATCAATGGAACAATGTCACAACAAACTTAATGATGTGGGTGGTACTATTAATAATTT TGAGGTTTGCTAGGCATAAAATAACAAAGCCAATTTAATAGGTCTAAAAAACAATAAGAC TGTGTTAAAAGTACATTTTTAACTGCTATTAGTGTTTTTCCCATATACTTGTTAATAATT TATATTTCTCTCTTTAATGGTCTTTCCCTTTTAAACTATTAAGGGCCTGAGGATTTTCTG TTACATTTGAATGAACTCTTTCATGCTATATGTAAATATTTTCCTAGTCTATTGTTCTTT TAATTTTAATTTTTCATAGTTTAAAAAAATTTTAGGCTAGGCACGGTGGCTCATGCCTGT AACCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAAGAGATCGAGACTAT CCTGGCCAACATGGTGAAACCCGGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGT GGCGTGTGCCTGTATAGTCCTAGCTACTTGGGAGGCTGAGGCAGAGGCAGAAGAATCGCT TGAACACAGGAGGCAGAGGTTGCGGCCAGCTGAGATCGCGCCATTGCACTCCAGCCTGGG TGGCAGAGCAAGACTTTGACTCAAAAAATAATAATAATAAATTTTAATCTCTTTCTGGCT GAATTCATCATTTTTTTCTTTGTTCACTGTCCTTTCGACATTGATGTATATAAGGTGATA CATTATGACTGCTCAATGATAATAGACAATGATCGTTGTCATAATAATAAAAATCATGCT GGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGTGAGGCCGAGGTGAGTGGATCAT GAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAAT ACAAAAATTAGCCGGGCATGGTGGTGCGCGTCTGTAGTCCCAGCTACTCAGGAGGCTGAG GCAGGAGAATTGCTTGAACCCGGGAGGCAGAGGCTGCAGTGAGCTGAGATCGCGCCACTG CACTCCAGCCTGGGCAATAGAGCAAGACTCCATCTCAAATAATAATAATAATAATTTCAG AGGGCCTCATTATACTTGCGAAACATGGGGTTTATGAAAATTCTAGGAAGGGGAGTAATG AAGTGGATACCTCTTGAGAGTGTATAGGAAACTATGAGTATGTACTGGCAGGAGGGAAAG AGGAAGAAGAGAGAGGGCCAGTTTCCTTCCTCTGTCAAGGCATGACAGCATGTCTCAGAG CACGATGTACACTTAACACGTAGGCAGAAAATGGCTTTCTTAGGCAGTCTTTCAAATGAA ATCCCCCTGGCTGGTGGTATTCATCTGCTTTGCCAGTGATGCTCATAAAATGATTCCAAG GCACCGCAGAGCTCTCGAGTCACTCCCAACTATCAAAGAGTTATGCTCGGTTTACATTTC AATATTAGTTACACTGGGCTCTGAGCTACTTGCAGGCATTTGTAACCCCAAGGTTCTGAA ACCTGTAAGGTGAAGACGTAAATGTTTGCCAGATGACCATTTGAAAAAATTATTTTAACA ATTTTCTAATTCTTTTGGCACTTGTTTGGAAATGTATGGAGTGGAAAGAAGTAGGGTGTT CACATTCTCATCCAAGTCCAGGCACCAACGGGTTGGCTAATCTTAGATAACTTATTTTTC TGGGCCTCGATTTCCTCATTTGTTAAAATAATGGAGGGCTTCAGGCTAGATGATCTCAGA GATAGTTTTTGGTGAGGATTATTTGACTACAGATTGTAAATTAACTAAATAAAATGTCCA GTTAATTGGGTTATCCTATATTTTTAAAACTATGTCTGATCACAAAGAGAGTAGATTATA AAATAAACTATCAACCTTTTCATAGCTTCAAAGGTATTAGTTTAATTTGGATTTACTGTG AGTTCTCATGATTTTCAATACAATGCAGTTTACAGTATAATATAATTCATATTACAAATA TAAGTGCATTGAAATCAATGTTGGACAATTGAACAAGAACGAGAAAAAAAAAGGCTTTCT ATCCTCTAGAGCTGTGCTTGCTGTCCACTATGGAAGTGAAATGTGGCTAGTCTGAATTAA GATGTACTGTTAAGTACTAAATACTCATTGGATTTCGAAGGTTTGTTATGAAAAAAGAAT ATCTCATTAATGATTTTATACTGATTACATATTAAAATAAAAATAACTCTAAAACTATCC TAAAAGTTAGTTTTATCTATTTTTTTACTTTGTAAAATATGGCTACAAAAAAATTTAAAT TACAGACGTAGGTCACACTGTATTTCTGTTAGATGCTGCTGCTTAACAGGGGTAGAAGGG GTAGAAGATTAACTATTTGCACTATTTAAATGAAAATATTTTTGCTTTTTATTCCAGCAT ACTTAATCTCCAATGATGTTTAAAGTGTTAAATTTATTCTTTTATAGGAAAATGGCTTTG TAAAGAAGTTTGAACCTAAATCTGGCTGGATGACTTTTCTAGAAGTTACAGGAAAGATCT GTGAAATGCTATCTCTCCTGAAGCAATACTGTTGACCAGAAAGGACACTCCATATTGTGA AACCGGCCTAATTTTTCTGACTGATATGGAAACGATTGCCAACACATACTTCTACTTTTA AATAAACAACTTTGATGATGTAACTTGACCTTCCAGAGTTATGGAAATTTTGTCCCCATG TAATGAATAAATTGTATGTATTTTTCTCTATA OMIM ID 601056