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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TRIM27 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5987
Official gene symbolTRIM27
Full nametripartite motif-containing 27
Aliases,RFP,RNF76,
Gene summaryThis gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein. [provided by RefSeq]
LocationChromosome: 6   Locus: 6p22
Gene position28891768 - 28870779  Map Viewer
Gene orientationminus
Gene size20990 bp
Gene sequence
OMIM ID602165