Entrez gene ID | | 5989 |
Official gene symbol | | RFX1 |
Full name | | regulatory factor X, 1 (influences HLA class II expression) |
Aliases | | ,EFC,RFX, |
Gene summary | | This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.1 |
Gene position | | 14117134 - 14072342 Map Viewer |
Gene orientation | | minus |
Gene size | | 44793 bp |
Gene sequence |
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OMIM ID | | 600006 |
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