Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for RFX1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID5989
Official gene symbolRFX1
Full nameregulatory factor X, 1 (influences HLA class II expression)
Aliases,EFC,RFX,
Gene summaryThis gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.1
Gene position14117134 - 14072342  Map Viewer
Gene orientationminus
Gene size44793 bp
Gene sequence
OMIM ID600006