Entrez gene ID | | 6001 |
Official gene symbol | | RGS10 |
Full name | | regulator of G-protein signaling 10 |
Aliases | | ,-, |
Gene summary | | Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 10 Locus: 10q25 |
Gene position | | 121302222 - 121259339 Map Viewer |
Gene orientation | | minus |
Gene size | | 42884 bp |
Gene sequence |
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