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Gene information for RGS10 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6001
Official gene symbolRGS10
Full nameregulator of G-protein signaling 10
Aliases,-,
Gene summaryRegulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q25
Gene position121302222 - 121259339  Map Viewer
Gene orientationminus
Gene size42884 bp
Gene sequence