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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BCL6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID604
Official gene symbolBCL6
Full nameB-cell CLL/lymphoma 6
Aliases,BCL5,BCL6A,LAZ3,ZBTB27,ZNF51,
Gene summaryThe protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3q27
Gene position187463513 - 187439165  Map Viewer
Gene orientationminus
Gene size24349 bp
Gene sequence
OMIM ID109565