Entrez gene ID | | 60436 |
Official gene symbol | | TGIF2 |
Full name | | TGFB-induced factor homeobox 2 |
Aliases | | ,-, |
Gene summary | | The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q11.2-q12 |
Gene position | | 35202010 - 35222353 Map Viewer |
Gene orientation | | plus |
Gene size | | 20344 bp |
Gene sequence |
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