Entrez gene ID | | 605 |
Official gene symbol | | BCL7A |
Full name | | B-cell CLL/lymphoma 7A |
Aliases | | ,BCL7, |
Gene summary | | This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12q24.13 |
Gene position | | 122459861 - 122499950 Map Viewer |
Gene orientation | | plus |
Gene size | | 40090 bp |
Gene sequence |
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OMIM ID | | 601406 |
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