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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BCL7A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID605
Official gene symbolBCL7A
Full nameB-cell CLL/lymphoma 7A
Aliases,BCL7,
Gene summaryThis gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.13
Gene position122459861 - 122499950  Map Viewer
Gene orientationplus
Gene size40090 bp
Gene sequence
OMIM ID601406