Entrez gene ID | | 60676 |
Official gene symbol | | PAPPA2 |
Full name | | pappalysin 2 |
Aliases | | ,PAPP-A2,PAPPE,PLAC3, |
Gene summary | | This gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23-q25 |
Gene position | | 176432307 - 176811972 Map Viewer |
Gene orientation | | plus |
Gene size | | 379666 bp |
Gene sequence |
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