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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PAPPA2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID60676
Official gene symbolPAPPA2
Full namepappalysin 2
Aliases,PAPP-A2,PAPPE,PLAC3,
Gene summaryThis gene encodes a member of the pappalysin family of metzincin metalloproteinases. The encoded protein cleaves insulin-like growth factor-binding protein 5 and is thought to be a local regulator of insulin-like growth factor (IGF) bioavailability. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q23-q25
Gene position176432307 - 176811972  Map Viewer
Gene orientationplus
Gene size379666 bp
Gene sequence