Entrez gene ID | | 608 |
Official gene symbol | | TNFRSF17 |
Full name | | tumor necrosis factor receptor superfamily, member 17 |
Aliases | | ,BCM,BCMA,CD269, |
Gene summary | | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p13.1 |
Gene position | | 12058964 - 12061925 Map Viewer |
Gene orientation | | plus |
Gene size | | 2962 bp |
Gene sequence |
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OMIM ID | | 109545 |
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